中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Immune modulation for the patterns of epithelial cell death in inflammatory bowel disease
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2025, 卷号: 154, 页码: 13
作者:
Jiang, Yuting
;
Chen, Jie
;
Du, Yaoyao
;
Fan, Minwei
;
Shen, Lan
  |  
收藏
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浏览/下载:0/0
  |  
提交时间:2025/06/23
Inflammatory bowel disease
Mucosal barrier
Epithelium
Immune cells
De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17
作者:
Zhou, Huiling
;
Hou, Bo
;
Shan, Yiming
;
Huang, Lujia
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras
Tumor microenvironment
Tumor-specific PD-L1 degradation
Geriatric Nutritional Risk Index is an effective prognostic predictor for metastatic/recurrent or unresectable esophageal cancer receiving immunotherapy
期刊论文
OAI收割
JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2025, 卷号: 16, 期号: 1, 页码: 22
作者:
Wang, Bei
;
Wang, Zixuan
;
Xu, Chuanhai
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/05/27
Geriatric Nutritional Risk Index (GNRI)
esophageal squamous cell carcinoma (ESCC)
immune checkpoint inhibitors (ICIs)
programmed cell death ligand 1 (PD-L1)
The interaction between central and peripheral immune systems in methamphetamine use disorder: current status and future directions
期刊论文
OAI收割
JOURNAL OF NEUROINFLAMMATION, 2025, 卷号: 22, 期号: 1, 页码: 14
作者:
Shi, Sai
;
Sun, Yiwen
;
Zan, Guiying
;
Zhao, Min
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Methamphetamine
Immune system
Neuroinflammation
Substance use disorder
Design, synthesis and pharmacological evaluation of 1,2,3,4-tetrahydrobenzofuro[2,3-c] pyridine derivatives as p21-activated kinase 4 inhibitors for treatment of pancreatic cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 1, 页码: 438-466
作者:
Li, Yang
;
Fang, Yan
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/04/01
P21-activated kinase 4
Tetrahydrobenzofuro[2
3-c]pyridine
Structure-activity relationship
Allosteric inhibitor
Pharmacokinetics properties
Kinase selectivity
Pancreatic cancer
Immune infiltration
Discovery of a non-nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect
期刊论文
OAI收割
MEDCOMM, 2025, 卷号: 6, 期号: 1, 页码: e70001
作者:
Wang, Xiyuan
;
Zhan, Zhengsheng
;
Wang, Zhen
;
Zhang, Yan
;
Zhao, Kaiyan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/04
antitumor
immune memory
innate immunity
STING agonist
Exploring the innate immune system of Urechis unicinctus: Insights from full-length transcriptome analysis
期刊论文
OAI收割
GENE, 2024, 卷号: 928, 页码: 16
作者:
Dong, Haomiao
;
Huang, Dong
;
Zhang, Jian
;
Xu, Dong
;
Jiao, Xudong
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/10/24
Urechis unicinctus
SMRT sequencing
Full-length transcriptome
Immune-related molecules
Pattern recognition receptors
PoCXCL8, a teleost chemokine, exerts direct bactericidal, chemotactic/ phagocytic, and NETs releasing properties, promoting host anti-bacterial immunity
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2024, 卷号: 154, 页码: 12
作者:
Zhao, Kun-yu
;
Chen, Guan-yu
;
Huang, Hui
;
Jiao, Xu-dong
;
Li, Xue-peng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/10/24
Paralichthys olivaceus
CXCL8
Antibacterial immune
Leukocyte vitality
Integrated omics profiling reveals systemic dysregulation and potential biomarkers in the blood of patients with neuromyelitis optica spectrum disorders
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 18
作者:
Xie, Zuoquan
;
Zhou, Qinming
;
Hu, Jin
;
He, Lu
;
Meng, Huangyu
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/12/11
Neuromyelitis optica spectrum disorders
Blood immune cells phenotyping
Plasma cytokine array
Plasma metabolomics
Biomarker
Dynamic polyphenol nanoparticles boost cuproptosis-driven metalloimmunotherapy of breast cancer
期刊论文
OAI收割
NANO TODAY, 2024, 卷号: 58, 页码: 12
作者:
Zhang, Huijuan
;
Chen, Fangmin
;
Cheng, Wenhao
;
Lai, Yi
;
Hou, Bo
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/10/09
Polyphenol
Cuproptosis
Dynamic covalent bond
Cancer metalloimmunotherapy
Tumor immune microenvironment