机构

• 上海药物研究所 [54]
• 昆明植物研究所 [17]
• 合肥物质科学研究院 [16]
• 上海生物化学与细胞... [15]
• 中国科学院大学 [7]
• 大连化学物理研究所 [6]
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采集方式

• OAI收割 [148]
• iSwitch采集 [9]

内容类型

• 期刊论文 [155]
• 会议论文 [1]
• 学位论文 [1]

发表日期

• 2025 [2]
• 2023 [10]
• 2022 [3]
• 2021 [9]
• 2020 [12]
• 2019 [7]
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学科主题

• Biochemist... [5]
• Pharmacolo... [5]
• Oncology [4]
• Genetics &... [3]
• Immunology [3]
• Biochemist... [2]
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筛选

浏览/检索结果: 共157条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response 期刊论文  OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19 作者:  Yao, Mingyue;  Yan, Wenzhong;  Wang, Yafang;  Zhao, Yu;  Xu, Xiaowei   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/04/01 Acute myeloid leukemia  HDAC inhibitor  FLT3-ITD mutation  DNA damage response  Synergistic effect  Drug resistance   Concurrent inhibition of p300/CBP and FLT3 enhances cytotoxicity and overcomes resistance in acute myeloid leukemia 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 14 作者:  Chen, Yu-jun;  Zhao, Yu;  Yao, Ming-yue;  Wang, Ya-fang;  Ma, Ming   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/04/01 acute myeloid leukemia  FLT3  p300/CBP  quizartinib resistance  combination strategy   Discovery of PRMT3 Degrader for the Treatment of Acute Leukemia 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 8 作者:  Zou, Wanyi;  Li, Mengna;  Wan, Shili;  Ma, Jingkun;  Lian, Linan   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/09/26 acute leukemia  MDM2  oxidative phosphorylation  PRMT3  PROTAC   Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18 作者:  Zhang, Jingyu;  Duan, Haiting;  Gui, Renzhao;  Wu, Mingfei;  Shen, Liteng   |  收藏  |  浏览/下载：135/0  |  提交时间：2023/12/19 Acute myeloid leukemia  Bromodomain-containing protein 9  Proteolysis-targeting chimera  Orally bioavailable  Docking   Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L 期刊论文  OAI收割 CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28 作者:  Li, Xin;  Wu, Xiaowei;  Nie, Shenyou;  Zhao, Jidong;  Yao, Yuan   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/12/19 MLL-rearranged leukemia  super elongation complexes  small-molecule inhibitor  protein-protein interaction  cancer therapeutics   CD71-mediated liposomal arsenic-nickel complex combined with all-trans retinoic acid for the efficacy of acute promyelocytic leukemia 期刊论文  OAI收割 ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 18, 期号: 4, 页码: 16 作者:  Liu, Xiao;  Zhang, Lili;  Yang, Yueying;  Yin, Weiwei;  Liu, Yunhu   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/10/17 Transferrin  Arsenic trioxide  Acute promyelocytic leukemia  Liposome  All-trans retinoic acid   Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 11 作者:  Wang, Han-lin;  Li, Jia-nan;  Kan, Wei-juan;  Xu, Gao-ya;  Luo, Guang-hao   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/10/17 acute myeloid leukemia  cytarabine  daunorubicin  idarubicin  drug resistant  multi-omics  autophagy  chloroquine phosphate   Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 14 作者:  Guo, Siqi;  Jia, Tongguan;  Xu, Xiaoming;  Yang, Feng;  Xiao, Senhao   |  收藏  |  浏览/下载：33/0  |  提交时间：2023/04/10 ENL Inhibitor  YEATS domain  Histone lysine acetylation  Benzimidazole derivatives  Acute myeloid leukemia   Design, synthesis, and evaluation of pyrido.[3,4-b]pyrazin-2(1H)-one derivatives as potent FLT3 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 79, 页码: 117155 作者:  Sun, Mei;  Wang, Chang;  Wang, Peipei;  Ye, Qingqing;  Zhou, Yubo   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/04/09 FLT3  FLT3-D835Y  Acute myeloid leukemia  Structure -activity relationships   Design, synthesis, and biological evaluation of BRD4 degraders 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 12 作者:  Ding, Mengyuan;  Shao, Yingying;  Sun, Danwen;  Meng, Suorina;  Zang, Yi   |  收藏  |  浏览/下载：34/0  |  提交时间：2023/04/10 PROTAC  BRD4 degradation  Leukemia  Multiple myeloma  Pulmonary fibrosis