机构

• 上海药物研究所 [15]
• 昆明植物研究所 [2]
• 大连化学物理研究所 [1]

采集方式

• OAI收割 [18]

内容类型

• 期刊论文 [18]

发表日期

• 2024 [2]
• 2023 [4]
• 2022 [1]
• 2021 [2]
• 2020 [3]
• 2019 [1]
• 更多

学科主题

• Plant Scie... [1]

筛选

浏览/检索结果: 共18条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Mass balance, metabolism, and pharmacokinetics of [14C]amdizalisib, a clinical-stage novel oral selective PI3Kδ inhibitor for the treatment of non-hodgkin's lymphoma, in healthy Chinese volunteers 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13 作者:  Zhao, Chun-Yang;  Zhang, Li-Jun;  Sun, Chan;  Yu, Cheng-Yin;  Wang, Jian   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/01/06 amdizalisib  PI3K delta kinase  metabolism  mass balance  metabolite identification  pharmacokinetics  safety   Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS 期刊论文  OAI收割 XENOBIOTICA, 2024, 页码: 9 作者:  Yuan, Yali;  Wang, Weiqiang;  Luo, Jing;  Tang, Chongzhuang;  Zheng, Yuandong   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/02/19 peptide-drug conjugate  PDC  LN005  metabolite identification  liver S9s   Pharmacokinetic and metabolite profile of orally administered anemoside B4 in rats with an improved exposure in formulations of rectal suppository 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 315, 页码: 11 作者:  Ye, Yaqing;  Xue, Mingzhen;  Tian, Xiaoting;  Gao, Hongwei;  Hu, Pei   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 Anemoside B4  Pulsatilla chinensis  metabolite identification  Pharmacokinetics  Rectal suppository   Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221 作者:  He Yifei;  Liu Yin;  Yu Jinghua;  Cheng Huan;  Odilov Abdullajon   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/05/22 TPN171  14CTPN171  PDE5 inhibitor  pulmonary arterial hypertension  healthy volunteers  pharmacokinetics  metabolite identification  mass balance   Metabolic and transcriptomic analyses elucidate a novel insight into the network for biosynthesis of carbohydrate and secondary metabolites in the stems of a medicinal orchid Dendrobium nobile 期刊论文  OAI收割 PLANT DIVERSITY, 2023, 卷号: 45, 期号: 3, 页码: 326-336 作者:  Zhang,Yu-Wen;  Shi,Yu-Cen;  Zhang,Shi-Bao   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/07/17 Dendrobium nobile  Transcriptome  Metabolome  Polysaccharides  Alkaloids  Secondary metabolite biosynthesis  POLYSACCHARIDES  GENES  OFFICINALE  IDENTIFICATION  TIME   Machine learning-assisted structure annotation of natural products based on MS and NMR data 期刊论文  OAI收割 NATURAL PRODUCT REPORTS, 2023, 卷号: 40, 期号: 11, 页码: 1735-1753 作者:  Hu,Guilin;  Qiu,Minghua   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/07/10 H-1-NMR CHEMICAL-SHIFTS  STRUCTURE-BASED PREDICTIONS  TANDEM MASS-SPECTRA  STRUCTURE ELUCIDATION  NEURAL-NETWORK  METABOLITE IDENTIFICATION  COMP   Pharmacokinetics, mass balance, and metabolism of [C-14]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13 作者:  He, Yi-fei;  Liu, Yin;  Yu, Jing-hua;  Cheng, Huan;  Odilov, Abdullajon   |  收藏  |  浏览/下载：42/0  |  提交时间：2022/08/16 TPN171  [C-14]TPN171  PDE5 inhibitor  pulmonary arterial hypertension  healthy volunteers  pharmacokinetics  metabolite identification  mass balance   Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439 期刊论文  OAI收割 ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893 作者:  Shackleford, David M.;  Chiu, Francis C. K.;  Katneni, Kasiram;  Blundell, Scott;  McLaren, Jenna   |  收藏  |  浏览/下载：54/0  |  提交时间：2021/11/04 OZ439 (artefenomel)  malaria  metabolite identification  cytochrome P450 metabolism  cytochrome P450 inhibition  time-dependent inhibition   p Metabolite Identification in the Preclinical and Clinical Phase of Drug Development 期刊论文  OAI收割 CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 11, 页码: 838-857 作者:  Wu, Yali;  Pan, Lulu;  Chen, Zhendong;  Zheng, Yuandong;  Diao, Xingxing   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/06/15 Metabolite identification  drug toxicity  drug exposure  covalent-binding drug  drug safety  natural medicines   Systematic comparison of metabolic differences of Uncaria rhynchophylla in rat, mouse, dog, pig, monkey and human liver microsomes 期刊论文  OAI收割 ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 页码: 7 作者:  Li, Hao-Jv;  Wei, Wen-Long;  Li, Zhen-Wei;  Yao, Chang-Liang;  Wang, Meng-Yuan   |  收藏  |  浏览/下载：48/0  |  提交时间：2020/12/24 Uncaria rhynchophylla  Indole alkaloids  Mass defect filter  Time-staggered targeted ion lists  Metabolite identification  Liver microsomes