中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
金属研究所 [2]
上海药物研究所 [2]
化学研究所 [1]
过程工程研究所 [1]
采集方式
OAI收割 [6]
内容类型
期刊论文 [6]
发表日期
2024 [2]
2014 [1]
2012 [2]
2009 [1]
学科主题
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Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 3286-3290
作者:
Zheng, Miao
;
Feng, Bo
;
Zhang, Yumin
;
Liu, Xin
;
Zhao, Na
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/08/22
Non-covalent PLpro inhibitors
Antiviral activity
Structural-based drug design
Imidazo[4,5-b]pyridine scaffold
Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17
作者:
Lan, Yaohan
;
Peng, Xia
;
Ji, Yinchun
;
Su, Yi
;
Duan, Wenhu
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/02/27
AXL inhibitor
In vivo antitumor efficacy
6-Naphthyridin-4-one derivatives
Scaffold hopping
Structure-based drug design
Effects of cryopreservation on human mesenchymal stem cells attached to different substrates
期刊论文
OAI收割
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2014, 卷号: 8, 期号: 8, 页码: 664-672
作者:
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2014/09/30
human mesenchymal stem cells
tissue engineering
cell attachment
cryopreservation
cell recovery
scaffold design
Computer aided modeling and pore distribution of bionic porous bone structure
期刊论文
OAI收割
JOURNAL OF CENTRAL SOUTH UNIVERSITY, 2012, 卷号: 19, 期号: 12, 页码: 3492-3499
作者:
Li Hu
;
Yang Jianyu
;
Su Pengcheng
;
Wang Wanshan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2021/02/02
FINITE-ELEMENT
TISSUE
SCAFFOLD
DESIGN
CELLS
tissue scaffold
geometry modeling
porous structure
compute aided design
optimal design
clinic implants
Computer aided modeling and pore distribution of bionic porous bone structure
期刊论文
OAI收割
JOURNAL OF CENTRAL SOUTH UNIVERSITY, 2012, 卷号: 19, 期号: 12, 页码: 3492-3499
作者:
Li Hu
;
Yang Jianyu
;
Su Pengcheng
;
Wang Wanshan
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/02/02
FINITE-ELEMENT
TISSUE
SCAFFOLD
DESIGN
CELLS
tissue scaffold
geometry modeling
porous structure
compute aided design
optimal design
clinic implants
A Novel Method for Enzyme Design
期刊论文
OAI收割
JOURNAL OF COMPUTATIONAL CHEMISTRY, 2009, 卷号: 30, 期号: 2, 页码: 256-267
作者:
Zhu, Xiaolei
;
Lai, Luhua
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/04/09
Enzyme Design
Vector Matching
Active Site Residues
Coslscore
Triose Phosphate Isomerase
Protein Scaffold
Side-chain Packing