中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
近代物理研究所 [1]
采集方式
OAI收割 [5]
内容类型
期刊论文 [5]
发表日期
2022 [1]
2019 [1]
2015 [3]
学科主题
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Identification of PRMT5 inhibitors with novel scaffold structures through virtual screening and biological evaluations
期刊论文
OAI收割
JOURNAL OF MOLECULAR MODELING, 2022, 卷号: 28, 期号: 7, 页码: 184
作者:
Zhang, Qian
;
Zhang, Lun
;
Jin, Jia
;
Fan, Yaohua
;
Wang, Xiaoguang
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/03/21
PRMT5
Small-molecule inhibitors
Virtual screening
Molecular docking
Molecular dynamics simulations
Computational Insight Into the Small Molecule Intervening PD-L1 Dimerization and the Potential Structure-Activity Relationship
期刊论文
OAI收割
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 15
作者:
Shi, Danfeng
;
An, Xiaoli
;
Bai, Qifeng
;
Bing, Zhitong
;
Zhou, Shuangyan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/19
PD-L1
small-molecule inhibitors
molecular dynamics simulation
metadynamics simulation
R-group QSAR
Toll-like receptors: potential targets for lupus treatment
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 12, 页码: 1395-1407
作者:
Wu, Yan-wei
;
Tang, Wei
;
Zuo, Jian-ping
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
systemic lupus erythematosus
autoimmune diseases
Toll-like receptors
TLR antagonists
immune modulatory oligonucleotides
small molecular inhibitors
antibodies
miRNAs
tolllikereceptorspotentialtargetsforlupustreatment
期刊论文
OAI收割
actapharmacologicasinica, 2015, 卷号: 36, 期号: 12, 页码: 1395
作者:
Wu Yanwei
;
Tang Wei
;
Zuo Jianping
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
PATTERN-RECOGNITION RECEPTORS
ALPHA MONOCLONAL-ANTIBODY
AUTOREACTIVE B-CELLS
I INTERFERON
DENDRITIC CELLS
AUTOANTIBODY PRODUCTION
RHEUMATOID-ARTHRITIS
PHASE-I
KINASE-ACTIVITY
MESSENGER-RNAS
systemic lupus erythematosus
autoimmune diseases
Toll-like receptors
TLR antagonists
immune modulatory oligonucleotides
small molecular inhibitors
antibodies
miRNAs
policresulenanovelns2bns3proteaseinhibitoreffectivelyinhibitsthereplicationofdenv2virusinbhk21cells
期刊论文
OAI收割
actapharmacologicasinica, 2015, 卷号: 36, 期号: 9, 页码: 1126
作者:
Wu Dengwei
;
Mao Fei
;
Ye Yan
;
Li Jian
;
Xu Chuanlian
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2020/07/01
SMALL-MOLECULE INHIBITORS
STRUCTURE-BASED DISCOVERY
DRUG-LIKE MOLECULES
DENGUE VIRUS
SERINE-PROTEASE
NS3 PROTEASE
PEPTIDE INHIBITORS
NS2B-NS3 PROTEASE
ACCURATE DOCKING
IN-VITRO
Dengue virus
antiviral drug
NS2B/NS3 protease
policresulen
molecular docking
molecular modeling