中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
成都生物研究所 [1]
武汉病毒研究所 [1]
上海生物化学与细胞生... [1]
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OAI收割 [20]
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期刊论文 [21]
发表日期
2024 [1]
2009 [1]
2008 [1]
2004 [2]
2003 [2]
2002 [4]
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Chemistry,... [1]
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Design, Synthesis, and Biological Evaluation of Novel Tetrahydroacridin Hybrids with Sulfur-Inserted Linkers as Potential Multitarget Agents for Alzheimer's Disease
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 8, 页码: 17
作者:
Wu, Xiuyuan
;
Ze, Xiaotong
;
Qin, Shuai
;
Zhang, Beiyu
;
Li, Xinnan
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2024/06/27
Alzheimer's disease
tacrine
cystamine
MTDLs
inhibitors
molecular modeling
Facile synthesis of novel tacrine analogues
期刊论文
OAI收割
JOURNAL OF CHEMICAL RESEARCH-S, 2009, 期号: 9, 页码: 562_564
作者:
Hu, HA
;
Zhang, AJ
;
Ding, LS
;
Hu, HA, Taizhou Univ, Coll Pharmaceutial & Chem Engn, Linhai 317000, Peoples R China.
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2011/07/08
Tacrine
Pyrazoles
4-aminoquinolines
4-aminopyridines
Tin(Iv) Chloride
Bis(7)-tacrine, a promising anti-Alzheimer's dimer, affords dose- and time-dependent neuroprotection against transient focal cerebral ischemia
期刊论文
OAI收割
NEUROSCIENCE LETTERS, 2008, 卷号: 439, 期号: 2, 页码: 160-164
作者:
Zhao, YM
;
Li, WM
;
Chow, PCY
;
Lau, DTK
;
Lee, NTK
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2015/07/22
bis(7)-tacrine
cerebral ischemia
stroke
multiple targets
memantine
Synthesis and evaluation of tacrine-E2020 hybrids as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 卷号: 14, 期号: 18, 页码: 4639-4642
作者:
Shao, D
;
Zou, CY
;
Luo, C
;
Tang, XC
;
Li, YC
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
tacrine-E2020
hybrids
acetylcholinesterase inhibitor
Alzheimer's disease
Tetrahydroacridine inhibits voltage-dependent Na+ current in guinea-pig ventricular myocytes
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2004, 卷号: 25, 期号: 9, 页码: 1138-1144
作者:
Wang, W
;
Wang, YP
;
Hu, GY
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Alzheimer disease
cholinesterase inhibitors
sodium channels
tetrahydroacridine (tacrine)
myocardium
patch-clamp techniques
Acute effects of huperzine A and tacrine on rat liver
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2003, 卷号: 24, 期号: 3, 页码: 247-250
作者:
Ma, XC
;
Xin, J
;
Wang, HX
;
Zhang, T
;
Tu, ZH
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
cholinesterase inhibitors
huperzine A
tacrine
liver
acute toxicity test
effectsofhuperzineaonlivercytochromep450inrats
期刊论文
OAI收割
actapharmacologicasinica, 2003, 卷号: 24, 期号: 8, 页码: 831
作者:
Ma Xiaochao
;
Wang Haixue
;
Xin Jian
;
Zhang Ting
;
Tu Zenghong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
ALZHEIMERS-DISEASE
OXIDATION
ENZYMES
MICROSOMES
CHEMICALS
TACRINE
huperzine A
cytochrome P-450
cytochrome P-450CYP1A2
liver
rat
Effects of huperzine A on acetylcholinesterase isoforms in vitro: comparison with tacrine, donepezil, rivastigmine and physostigmine
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2002, 卷号: 455, 期号: 2-3, 页码: 101-107
作者:
Qin, Z
;
Xi, CT
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
acetylcholinesterase isoform
huperzine A
tacrine
donepezil
rivastigmine
physostigmine
Alzheimer's disease
(rat)
Tacrine attenuates hydrogen peroxide-induced apoptosis by regulating expression of apoptosis-related genes in rat PC12 cells
期刊论文
OAI收割
MOLECULAR BRAIN RESEARCH, 2002, 卷号: 107, 期号: 1, 页码: 1-8
作者:
Wang, R
;
Zhou, J
;
Tang, XC
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收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
tacrine
oxidative stress
apoptosis
apoptosis-related genes
PC12 cells
Huperzine A inhibits the sustained potassium current in rat dissociated hippocampal neurons
期刊论文
OAI收割
NEUROSCIENCE LETTERS, 2002, 卷号: 329, 期号: 2, 页码: 153-156
作者:
Li, Y
;
Hu, GY
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Alzheimer's disease
cholinesterase inhibitor
hippocampus
huperzine A
sustained potassium current
tacrine