中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [19]
合肥物质科学研究院 [6]
金属研究所 [3]
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上海营养与健康研究所 [1]
长春应用化学研究所 [1]
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OAI收割 [31]
内容类型
期刊论文 [31]
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2022 [2]
2021 [3]
2020 [3]
2019 [2]
2017 [2]
2016 [2]
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Chemistry [3]
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Baseline anemia predicts a poor prognosis in patients with non-small cell lung cancer with epidermal growth factor receptor mutations: a retrospective study
期刊论文
OAI收割
BMC PULMONARY MEDICINE, 2022, 卷号: 22
作者:
Wei, Jingwen
;
Xiang, Jing
;
Hao, Yue
;
Si, Jinfei
;
Wang, Wenxian
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/12/22
Anemia
Epidermal growth factor receptor
Epidermal growth factor receptor tyrosine kinase inhibitors
Non-small cell lung cancer
Efficacy and safety of anlotinib with and without EGFR-TKIs or immunotherapy in the treatment of elder patients with non-small-cell lung cancer: a retrospective study
期刊论文
OAI收割
BMC PULMONARY MEDICINE, 2022, 卷号: 22
作者:
Wang, Wenxian
;
Shao, Lan
;
Xu, Yibing
;
Song, Zhengbo
;
Lou, Guangyuan
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/12/23
Non-small cell lung cancer
Prognosis
Angiogenesis
Tyrosine kinase inhibitors
The genomic landscape of young and old lung cancer patients highlights age-dependent mutation frequencies and clinical actionability in young patients
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF CANCER, 2021
作者:
Cai, Lei
;
Chen, Yong
;
Tong, Xiaoling
;
Wu, Xue
;
Bao, Hua
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2021/06/15
EGFR
ERBB2
gene fusions
tyrosine kinase inhibitors
young lung cancer patients
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:
Wu, Xiaowei
;
Dai, Mengdi
;
Cui, Rongrong
;
Wang, Yulan
;
Li, Chunpu
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
Tyrosine kinase
Covalent FGFR inhibitors
Virtual screening
Pyrazolo[3,4-d] pyridazinone
Structure-activity relationships
Antitumor efficacy
Treatment and Prognosis of Solid and Cystic Brain Metastases in Patients with Non-Small-Cell Lung Cancer
期刊论文
OAI收割
CANCER MANAGEMENT AND RESEARCH, 2021, 卷号: 13
作者:
Xu, Yi-Bing
;
Zhang, Yiping
;
Song, Zhengbo
;
Wang, Wenxian
;
Shao, Lan
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/09/06
cystic brain metastases
tyrosine kinase inhibitors
chemotherapy
radiation therapy
lung cancer
Characterization of covalent binding of tyrosine kinase inhibitors to plasma proteins
期刊论文
OAI收割
DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 35, 期号: 5, 页码: 456-465
作者:
Liu, Xiaoyun
;
Feng, Dan
;
Zheng, Mingyue
;
Cui, Yongmei
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/21
Covalent tyrosine kinase inhibitors
Covalent binding
Human serum albumin
Molecular docking
Quantitative calculations
Linear modeling
Species difference
Tumor Mutation Burden Correlates With Efficacy of Chemotherapy/Targeted Therapy in Advanced Non-Small Cell Lung Cancer
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:
Lin, Chen
;
Shi, Xun
;
Zhao, Jun
;
He, Qiong
;
Fan, Yun
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2020/10/26
tumor mutation burden (TMB)
clinical benefit
epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs)
chemotherapy
non-small cell lung cancer (NSCLC)
BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFR(T790M) mutation
期刊论文
OAI收割
THERANOSTICS, 2020, 卷号: 10, 期号: 14, 页码: 6122-6135
作者:
Yin, Weimin
;
Zhao, Yuge
;
Kang, Xuejia
;
Zhao, Pengfei
;
Zhao, Xuhong
  |  
收藏
  |  
浏览/下载:95/0
  |  
提交时间:2020/07/01
brain targeting delivery
tumor-associated macrophage
non-small cell lung cancer (NSCLC)
drug resistance
tyrosine kinase inhibitors (TKI)
EGFR T790M mutation
Discovery and Biological evaluation of pyrimido[4,5-d] pyrimidine-2,4(1H, 3H)-dione derivatives as potent Bruton's tyrosine kinase inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3390-3395
作者:
Diao, Yanyan
;
Fang, Xiaoyu
;
Song, Peiran
;
Lai, Mengzhen
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2020/07/01
Bruton's tyrosine kinase
B-cell malignancies
Potent inhibitors
Structure-activity relationship
Cellular activities
Mutational inactivation of mTORC1 repressor gene DEPDC5 in human gastrointestinal stromal tumors
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 45, 页码: 22746-22753
作者:
Pang, Yuzhi
;
Xie, Feifei
;
Liu, Xiaoxiao
;
Lu, Xiaojing
;
Li, Ke
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/09
sarcoma
GIST
KIT tyrosine kinase inhibitors
DEPDC5