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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [669]
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OAI收割 [669]
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期刊论文 [669]
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2024 [17]
2023 [31]
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2020 [31]
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Chemistry [28]
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共669条,第1-10条
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内容类型:期刊论文
专题:上海药物研究所
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Absorption, distribution, metabolism and excretion of linaprazan glurate in rats
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 242, 页码: 10
作者:
Zhang, Xinyue
;
Liu, Donghui
;
Lu, Ming
;
Yuan, Yali
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Linaprazan glurate
[14C]linaprazan glurate
Linaprazan
ADME
Radio-labeling
P-CAB
Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
期刊论文
OAI收割
DIABETES OBESITY & METABOLISM, 2024, 页码: 9
作者:
Bian, Yi-cong
;
Meng, Jian
;
Hu, Tao
;
Ma, Sheng
;
Huang, Chen-rong
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
HSK7653
long-acting dipeptidyl peptidase-4 inhibitor
mass balance
metabolism
pharmacokinetics
radiolabelled
Integrated multi-omics analysis reveals gut microbiota dysbiosis and systemic disturbance in major depressive disorder
期刊论文
OAI收割
PSYCHIATRY RESEARCH, 2024, 卷号: 334, 页码: 12
作者:
Xie, Zuoquan
;
Huang, Jingjing
;
Sun, Guangqiang
;
He, Shen
;
Luo, Zhiyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/22
Major depressive disorder
Peripheral changes
Gut microbiota
Immune phenotyping
Multiomics
Biomarkers
Pharmacokinetics, mass balance, and metabolism of [
14
C]envonalkib (TQ-B3139), a novel ALK tyrosine kinase inhibitor, in healthy Chinese subjects
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2024, 页码: 11
作者:
Ma, Sheng
;
Wang, Xin
;
Yan, Shu
;
Miao, Liyan
;
Wan, Xiaojing
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Envonalkib
TQ-B3139
Pharmacokinetics
Mass balance
Excretion
Metabolism
Chemical and biosynthetic potential of Penicillium shentong XL-F41
期刊论文
OAI收割
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 20, 页码: 597-606
作者:
Zou, Ran
;
Li, Xin
;
Chen, Xiaochen
;
Guo, Yue-Wei
;
Xu, Baofu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
genome analysis
indole terpene alkaloid
natural products
Penicillium
structure elucidation
Quantitative proteomics reveals the protective effects of Yinchenzhufu decoction against cholestatic liver fibrosis in mice by inhibiting the PDGFRβ/PI3K/AKT pathway
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Yinchenzhufu decoction
proteomics
cholestasis
liver fibrosis
PDGFR beta/PI3K/AKT
Pharmacokinetics and metabolite identification of 23-hydroxybetulinic acid in rats by using liquid chromatography-mass spectrometry method
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 10
作者:
Xue, Mingzhen
;
Yang, Cheng
;
Huang, Wensi
;
He, Yifei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
23-hydroxybetulinic acid
Pharmacokinetics
Metabolism
UPLC-MS
LC-MS/MS
Platanosides from Platanus x acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Wu, Xi-Ying
;
Zhao, Ze-Yu
;
Osman, Ezzat E. A.
;
Wang, Xiao-Juan
;
Choo, Yeun-Mun
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/06
Platanus x acerifolia
Platanosides
Molecular ion networking (MoIN)
Antibacterial
Staphylococcus aureus
Enterococcus faecium
Structure -activity relationship (SAR)
Molecular docking
Target validation
Transfer learning enhanced graph neural network for aldehyde oxidase metabolism prediction and its experimental application
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 2, 页码: 623-634
作者:
Xiong, Jiacheng
;
Cui, Rongrong
;
Li, Zhaojun
;
Zhang, Wei
;
Zhang, Runze
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Drug metabolism
Aldehyde oxidase
Transfer learning
Graph neural network
Kinase inhibitor
Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11
作者:
Wang, Weiqiang
;
Chen, Chong
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/01/16
LN005
Metabolism
Peptide -drug conjugates
UHPLC-HRMS
Doxorubicin