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浏览/检索结果: 共111条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Computationally Elucidating the Binding Kinetics for Different AChE Inhibitors to Access the Rationale for Improving the Drug Efficacy 期刊论文  OAI收割 JOURNAL OF PHYSICAL CHEMISTRY B, 2022, 页码: 9 作者:  Bai, Fang;  Jiang, Hualiang   |  收藏  |  浏览/下载：13/0  |  提交时间：2022/11/11 LC-MS/MS assay of fluoropezil and its two major metabolites in human plasma: an application to pharmacokinetic studies 期刊论文  OAI收割 BIOANALYSIS, 2022, 页码: 13 作者:  Guo, Runcong;  Hu, Jiafeng;  Jing, Jiao;  Liu, Ying;  Li, Jian   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/08/16 assay  bioanalysis  DC20  fluoropezil  LC-MS  MS  metabolites  pharmacokinetics   Novel inhibitors of AChE and A0 aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235, 页码: 22 作者:  Liu, Yulin;  Uras, Giuseppe;  Onuwaje, Itse;  Li, Wenlong;  Yao, Hong   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/08/16 Alzheimer's disease  Donepezil  Sulfone group  AChE inhibitor  Inhibiting A 0 aggregation  Neuroprotection   Design, synthesis, in vitro evaluation of a new pyrrolo[1,2-a]thiazolo[5,4-d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease 期刊论文  OAI收割 JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022, 页码: 16 作者:  Zeng, Yan;  Nie, Lifei;  Liu, Liu;  Niu, Chao;  Li, Yi   |  收藏  |  浏览/下载：27/0  |  提交时间：2022/06/15 Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 4, 页码: 1844-1855 作者:  Zhou, Yu;  Fu, Yan;  Yin, Wanchao;  Li, Jian;  Wang, Wei   |  收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24 Nematicidal activity of tirotundin and parthenolide isolated from Tithonia diversifolia and Chrysanthemum parthenium 期刊论文  OAI收割 JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES, 2021 作者:  Lan,Mingxian;  Gao,Xi;  Duan,Xiuan;  Li,Hongmei;  Yu,Hang   |  收藏  |  浏览/下载：41/0  |  提交时间：2022/04/02 Parthenolide  tirotundin  acetylcholinesterase  enzyme kinetics  toxic effects  SESQUITERPENE LACTONE  ANTICANCER  FLAVONOIDS  EXTRACT  ANALOG   Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519 作者:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li   |  收藏  |  浏览/下载：93/0  |  提交时间：2022/04/02 Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA   [1,5]-Hydride Shift-Cyclization versus C(sp(2))-H Functionalization in the Knoevenagel-Cyclization Domino Reactions of 1,4-and 1,5-Benzoxazepines 期刊论文  OAI收割 MOLECULES, 2020, 卷号: 25, 期号: 6, 页码: 19 作者:  Vargane, Dora Szaloki;  Toth, Laszlo;  Buglyo, Balazs   |  收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 domino Knoevenagel-[1  5]-hydride shift-cyclization  1  4-benzoxazepine  1  5-benzoxazepine  TDDFT-ECD calculation  acetylcholinesterase inhibitory activity   Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-A beta Aggregation Activity through Molecular Docking-Based Virtual Screening 期刊论文  OAI收割 CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 2, 页码: 161-166 作者:  Liu, Guangpu;  Jiao, Yang;  Lin, Yongqiang;  Hao, Haifang;  Dou, Yanli   |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 selective acetylcholinesterase inhibitor  amyloid beta aggregation  neuroprotectant  molecular docking  molecular dynamics simulation   Protein tyrosine phosphatase 1B (PTP1B) inhibitors from the deep-sea fungus Penicillium chrysogenum SCSIO 07007 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2020, 卷号: 96, 页码: 103646 作者:  Han, Wenrong;  Cai, Jia;  Zhong, Weimao;  Xu, Guangming;  Wang, Fazuo   |  收藏  |  浏览/下载：39/0  |  提交时间：2020/09/22 Penicillium chrysogenum  alpha-pyrone  Indolyl diketopiperazine  Protein tyrosine phosphatase 1B inhibition