中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
中国科学院大学 [3]
新疆理化技术研究所 [2]
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期刊论文 [23]
学位论文 [3]
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Clinical correlates and thyroid hormones of metabolic syndrome in first-episode and drug-na & iuml;ve major depressive disorder outpatients with and without hyperglycemia: a comprehensive cross-sectional study
期刊论文
OAI收割
BMC PSYCHIATRY, 2023, 卷号: 23, 期号: 1, 页码: 8
作者:
Zheng, Siyang
;
Wang, Zhiyang
;
Yang, Limin
;
Zhang, Xiangyang
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/09
Major depressive disorder
Hyperglycemia
Metabolic syndrome
Anti-thyroglobulin
Thyroid-stimulating hormone
Phenotypic screening-based drug discovery of furan-2-carboxylic acid derivatives for the amelioration of type 2 diabetes mellitus (T2DM)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 246, 页码: 11
作者:
Chen, Lili
;
Huang, Suling
;
Ye, Yangliang
;
Shen, Yu
;
Xu, Tifei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
Phenotypic screening
Gluconeogenesis
Furan-2-carboxylic acid
T2DM
Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson
期刊论文
OAI收割
PHYTOCHEMISTRY, 2023, 卷号: 205, 页码: 9
作者:
Wang, Ai-Zhu
;
Han, Hua
;
Fang, Qiang-Qiang
;
Tan, Chang-Heng
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Hypericum acmosepalum
Hypericaceae
PPAPs
Anti -hyperglycemia
Hyperacmotones a -f
Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 14
作者:
Huang, Su-Ling
;
Xie, Wei
;
Ye, Yang-Liang
;
Liu, Jia
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/11/11
type 2 diabetes mellitus
coronarin A
glycogen synthesis
gluconeogenesis
mTORC1
IRS1
Design, synthesis and structural-activity relationship studies of phanginin A derivatives for regulating SIK1-cAMP/CREB signaling to suppress hepatic gluconeogenesis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 232, 页码: 14
作者:
Wu, Xing-De
;
Huang, Suling
;
Shi, Yu
;
Shen, Yu
;
Tu, Wen-Chao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/08/16
Hepatic gluconeogenesis
Type 2 diabetes
Phanginin A derivatives
SIK1
Structural-activity relationship
分子模拟应用于岩藻糖化糖胺聚糖 3D 结构确定及其与内源 性因子 X 酶的相互作用模式考察
学位论文
OAI收割
2021
作者:
陈鼎元
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/11/02
SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Ren, Yu-ran
;
Ye, Yang-liang
;
Feng, Ying
;
Xu, Ti-fei
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
SL010110
gluconeogenesis
primary mouse hepatocytes
PEPCK1
acetylation
degradation
天然萜类小分子调控脂肪细胞生成及改善动脉粥样硬化的研究
学位论文
OAI收割
2020
作者:
母蓉芳
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/11/02
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:
Zhou, Ting-ting
;
Zhao, Tong
;
Ma, Fei
;
Zhang, Yi-nan
;
Jiang, Jing
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
type 2 diabetes mellitus
hepatic gluconeogenesis
AMPK signaling pathway
(E)-3-(2-(quinoline-4-yl)vinyl)-1H-indol-6-ol (QVO)
4-[2-(1H-indol-3-yl)vinyl]quinoline (IVQ)
prodrug
Enteromorpha prolifera oligomers relieve pancreatic injury in streptozotocin (STZ)-induced diabetic mice
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2019, 卷号: 206, 页码: 403-411
作者:
Yuan, Xubing
;
Zheng, Junping
;
Ren, Lishi
;
Jiao, Siming
;
Feng, Cui
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/04/03
Enteromorpha prolifera oligomers
Antioxidation
Diabetes mellitus
Inflammation
Apoptosis