中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [182]
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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-32
作者:
I Hassan-Mohamed
  |  
收藏
  |  
浏览/下载:182/0
  |  
提交时间:2017/07/24
Eph Kinase
Ephrin
Small Molecules
Angiogenesis
Bile Acid
Lithocholic Acid
Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:13/0
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提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11
作者:
Wang, Weiqiang
;
Chen, Chong
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
LN005
Metabolism
Peptide -drug conjugates
UHPLC-HRMS
Doxorubicin
Human vascularized bile duct-on-a chip: a multi-cellular micro-physiological system for studying cholestatic liver disease
期刊论文
OAI收割
BIOFABRICATION, 2024, 卷号: 16, 期号: 1, 页码: 13
作者:
Du, Yu
;
de Jong, Iris E. M.
;
Gupta, Kapish
;
Waisbourd-Zinman, Orit
;
Har-Zahav, Adi
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收藏
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浏览/下载:61/0
  |  
提交时间:2023/11/28
microfluidic device
cholangiopathy
tissue engineering
organ-on-a-chip
primary sclerosing cholangitis
Obesity induced disruption on diurnal rhythm of insulin sensitivity via gut microbiome-bile acid metabolism
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2024, 卷号: 1869, 期号: 1, 页码: 13
作者:
Guo, Xiaozhen
;
Wang, Jiawen
;
Xu, Hualing
;
Wang, Yangyang
;
Cao, Yutang
  |  
收藏
  |  
浏览/下载:31/0
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提交时间:2024/01/16
Diurnal rhythm
Insulin sensitivity
Obesity
Gut microbiota
Ursodeoxycholic acid
Qing-Zhi-Tiao-Gan-Tang (QZTGT) prevents nonalcoholic steatohepatitis (NASH) by expression pattern correction
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 317, 页码: 14
作者:
Chu, Hang
;
Zhang, Weitao
;
Tan, Yan
;
Diao, Zhipeng
;
Li, Peng
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Fibrosis
Inflammation
Lipogenesis
NASH
QZTGT
TMNP
A fetal wound healing program after intrauterine bile duct injury may contribute to biliary atresia
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2023, 卷号: 79, 期号: 6, 页码: 13
作者:
de Jong, Iris E. M.
;
Hunt, Mallory L.
;
Chen, Dongning
;
Du, Yu
;
Llewellyn, Jessica
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/22
biliary atresia
hyaluronic acid
peribiliary glands
cholangiocyte
cholangiopathy
Absorption, Distribution, Metabolism, and Excretion of [
14
C]BS1801, a Selenium-Containing Drug Candidate, in Rats
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 24, 页码: 16
作者:
Yang, Cheng
;
Xue, Mingzhen
;
He, Yifei
;
Yin, Hanwei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
[C-14]BS1801
BS1801 (butaselen)
tissue distribution
metabolism
mass balance
selenium
Effects of glyphosate exposure on gut-liver axis: Metabolomic and mechanistic analysis in grass carp (Ctenopharyngodon idellus)
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 902, 页码: 12
作者:
Yan, Biao
;
Sun, Yumiao
;
Fu, Kaiyu
;
Zhang, Yindan
;
Lei, Lei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Glyphosate
Metabolomics
Grass carp
Gut-Liver axis
Saikosaponin D improves nonalcoholic fatty liver disease via gut microbiota-bile acid metabolism pathway
期刊论文
OAI收割
Food Science and Human Wellness, 2023
作者:
Li, Lan
;
Yang, Shengye
;
Liang, Xinyu
;
Liu, Yameng
;
Xu, Hualing
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/26
Gut Microbiota
Non-alcoholic Fatty Liver Disease
Ssd
Bile Acids
Farnesoid x Receptor