中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [84]
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期刊论文 [92]
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Exploration of the potential association between GLP-1 receptor agonists and suicidal or self-injurious behaviors: a pharmacovigilance study based on the FDA Adverse Event Reporting System database
期刊论文
OAI收割
BMC MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 13
作者:
Zhou, Jianxing
;
Zheng, You
;
Xu, Baohua
;
Long, Songjun
;
Zhu, Li-e
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/25
GLP-1RAs
Suicidal or self-injurious behaviors
Pharmacovigilance
FAERS database
Type 2 diabetes
Obesity
Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G
s
proteins
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 13
作者:
Cong, Zhaotong
;
Zhao, Fenghui
;
Li, Yang
;
Luo, Gan
;
Mai, Yiting
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/03/13
Tail engagement of arrestin at the glucagon receptor
期刊论文
OAI收割
NATURE, 2023, 页码: 21
作者:
Chen, Kun
;
Zhang, Chenhui
;
Lin, Shuling
;
Yan, Xinyu
;
Cai, Heng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
Conserved class B GPCR activation by a biased intracellular agonist
期刊论文
OAI收割
NATURE, 2023, 页码: 25
作者:
Zhao, Li-Hua
;
He, Qian
;
Yuan, Qingning
;
Gu, Yimin
;
He, Xinheng
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23
作者:
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Design and exploration of gut-restricted bifunctional molecule with TGR5 agonistic and DPP4 inhibitory effects for treating ulcerative colitis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 242, 页码: 114697
作者:
Han, Fanghui
;
Ning, Mengmeng
;
Wang, Kai
;
Gu, Yipei
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/21
Bifunctional molecule
Gut-restricted
Ulcerative colitis
TGR5
DPP4
Structure insights into selective coupling of G protein subtypes by a class B G protein-coupled receptor
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 13
作者:
Zhao, Li-Hua
;
Lin, Jingyu
;
Ji, Su-Yu
;
Zhou, X. Edward
;
Mao, Chunyou
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/04/10
Hepatic thyroid hormone signalling modulates glucose homeostasis through the regulation of GLP-1 production via bile acid-mediated FXR antagonism
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:
Yan, Ying
;
Niu, Zhoumin
;
Sun, Chao
;
Li, Peng
;
Shen, Siyi
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/12/13
Effects of site-directed mutagenesis of GLP-1 and glucagon receptors on signal transduction activated by dual and triple agonists
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13
作者:
Darbalaei, Sanaz
;
Chang, Ru-lue
;
Zhou, Qing-tong
;
Chen, Yan
;
Dai, An-tao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/09/30
glucagon-like peptide-1 receptor
glucagon receptor
dual and triple agonist
cAMP
pERK1/2
unimolecular polypharmacology
Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:
Zhong, Xian-Chun
;
Liu, Ya-Meng
;
Gao, Xiao-Xia
;
Krausz, Kristopher W.
;
Niu, Bing
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/08/16
nonalcoholic fatty liver disease
caffeic acid phenethyl ester
bile salt hydrolase
farnesoid X receptor
ceramide
gut microbiota