中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [174]
上海生物化学与细胞... [57]
合肥物质科学研究院 [44]
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期刊论文 [620]
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Breathing in danger: Unveiling the link between human exposure to outdoor PM
2.5
-bound polycyclic aromatic hydrocarbons and lung cancer risk in an urban residential area of China
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 907, 页码: 11
作者:
Famiyeh, Lord
;
Xu, Honghui
;
Chen, Ke
;
Tang, Yu-Ting
;
Ji, Dongsheng
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/02
Human exposure
Breathing
PAHs
Lung cancer
Urban
Residential area
Breathing in danger: Unveiling the link between human exposure to outdoor PM2.5 -bound polycyclic aromatic hydrocarbons and lung cancer risk in an urban residential area of China
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 907, 页码: 167762
作者:
Famiyeh, Lord
;
Xu, Honghui
;
Chen, Ke
;
Tang, Yu-Ting
;
Ji, Dongsheng
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/02/05
Human exposure
Breathing
PAHs
Lung cancer
Urban
Residential area
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
A validated LC-MS/MS method for the quantification of bevacizumab in rat, cynomolgus monkey, and human serum
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 11
作者:
Zhou, Ainan
;
Yu, Jinghua
;
Wu, Yali
;
Xue, Hao
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Monoclonal antibody
Bevacizumab
LC-MS
MS
Surrogate peptide
Pharmacokinetics
Serum
[
68
Ga]Ga-AUNP-12 PET imaging to assess the PD-L1 status in preclinical and first-in-human study
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2023, 页码: 11
作者:
Zhou, Ming
;
Xiang, Shijun
;
Zhao, Yajie
;
Tang, Yongxiang
;
Yang, Jinhui
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/11/16
PD-1/PD-L1
Immune checkpoints
PET/CT imaging
Immunotherapy
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14
作者:
Xu, Zhuo
;
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Zhu, Mengying
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Otilonium Bromide
Deubiquitinase
USP28
Selective inhibitor
Structure-based discovery of potent USP28 inhibitors derived from Vismodegib
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:
Zhou, Di
;
Xu, Zhuo
;
Huang, Yaodong
;
Wang, Hui
;
Zhu, Xiaoli
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
USP28
Structure-based
Vismodegib derivatives
Structure-activity relationships
c-Myc
Shape and Shear Stress Impact on the Toxicity of Mesoporous Silica Nanoparticles: In Vitro and In Vivo Evidence
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2023, 卷号: 20, 期号: 6, 页码: 3187-3201
作者:
Cheng, Yaxin
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
mesoporous silica nanoparticles (MSNs)
toxicity
shape
shear stress
in vitro blood flow model
Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 650, 页码: 117-122
作者:
Ni, Yicheng
;
Luo, Zhongyuan
;
Lv, Yixin
;
Ma, Shuyuan
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
Thioredoxin reductase 1 inhibitor
Chemical probe
High -throughput screening
Thimerosal
Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead
期刊论文
OAI收割
GENES & DISEASES, 2023, 卷号: 10, 期号: 2, 页码: 403-414
作者:
Li, Hui-yu
;
Qi, Wei-liang
;
Wang, Yu-xiang
;
Meng, Ling-hua
  |  
收藏
  |  
浏览/下载:117/0
  |  
提交时间:2023/10/17
Biomarkers
Covalent KRasG12Cinhibitors
Drug resistance
Human cancers
KRASG12Cmutation