中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [42]
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New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Zheng, Yingying
;
Lu, Li
;
Li, Mengyue
;
Xu, Dehua
;
Zhang, Laishun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Chromone
Thiazolidine-2
4-dione
Protein tyrosine phosphatase 1B
Inhibitors
Extraction of DNA from trace forensic samples with a modified lysis buffer and chitosan coated magnetic beads
期刊论文
OAI收割
FORENSIC SCIENCE INTERNATIONAL-GENETICS, 2023, 卷号: 67
作者:
Hu, Anzhong
;
Chen, Lin
;
Geng, Xuelei
;
Zhu, Ling
;
Liu, Yong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/11/10
Chitosan@Beads
Forensic biological evidence
STR loci
Trace DNA extraction
Inhibitors
Polymerase chain reaction (PCR)
Short tandem repeat (STR)
Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L
期刊论文
OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28
作者:
Li, Xin
;
Wu, Xiaowei
;
Nie, Shenyou
;
Zhao, Jidong
;
Yao, Yuan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
MLL-rearranged leukemia
super elongation complexes
small-molecule inhibitor
protein-protein interaction
cancer therapeutics
Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 378, 页码: 11
作者:
Yang, Yun
;
Xiong, Yuan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Human carboxylesterase 2 (hCES2A)
Berberine analogues
Structure -activity relationships (SAR)
Inhibition kinetics
Selectivity
Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 14
作者:
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
ENL Inhibitor
YEATS domain
Histone lysine acetylation
Benzimidazole derivatives
Acute myeloid leukemia
Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Wang, Zuo-wei
;
Zou, Feng-ming
;
Wang, Ao-li
;
Yang, Jing
;
Jin, Rui
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/22
AZD4547
RIPK1
inhibitors
SIRS model
anti-necroptosis
Cucumber (Cucumis sativus L.) Leaf Extract as a Green Corrosion Inhibitor for Carbon Steel in Acidic Solution: Electrochemical, Functional and Molecular Analysis
期刊论文
OAI收割
MOLECULES, 2022, 卷号: 27, 期号: 12, 页码: 18
作者:
Feng, Lijuan
;
Zhang, Shanshan
;
Hao, Long
;
Du, Hongchen
;
Pan, Rongkai
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/09/16
carbon steel
extract
green corrosion inhibitor
quantum chemical calculation
Novel inhibitors of AChE and A0 aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235, 页码: 22
作者:
Liu, Yulin
;
Uras, Giuseppe
;
Onuwaje, Itse
;
Li, Wenlong
;
Yao, Hong
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/08/16
Alzheimer's disease
Donepezil
Sulfone group
AChE inhibitor
Inhibiting A 0 aggregation
Neuroprotection
Effect of mixed inhibitor application on N2O production pathways in paddy soil
期刊论文
OAI收割
JOURNAL OF SOILS AND SEDIMENTS, 2022, 页码: 11
作者:
Wu, Kaikuo
;
Gong, Ping
;
Bai, Wei
;
Zhang, Zhe
;
Wei, Zhanbo
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/08/13
Inhibitors
Paddy soil
N2O production
Ammonia oxidation
Heterotrophic denitrification
Rapid screening of alpha-glucosidase inhibitors in Hypericum perforatum L. using bio-affinity chromatography coupled with UPLC/MS
期刊论文
OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2022
作者:
Dong, Q
;
Hu, N
;
Yue, HL
;
Wang, HL
;
Wei, Y
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/02