中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Diastereomers of Steroidal Alkaloids with Cytotoxic Activities against Non-Small-Cell Lung Cancer from the Bulbs of
Fritillaria sinica
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2024, 卷号: 87, 期号: 2, 页码: 252-265
作者:
Li, Jia-yuan
;
Wu, Shi-fei
;
An, Ya-ling
;
Yao, Chang-liang
;
Yao, Shuai
  |  
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2024/03/13
Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Lin, Ting-ting
;
Xiong, Wei
;
Chen, Gui-hua
;
He, Yang
;
Long, Li
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
osimertinib resistance
targeted drug delivery
liposomes
panobinostat
tumor-associated macrophage
combination therapy
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
A validated LC-MS/MS method for the quantification of bevacizumab in rat, cynomolgus monkey, and human serum
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 11
作者:
Zhou, Ainan
;
Yu, Jinghua
;
Wu, Yali
;
Xue, Hao
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Monoclonal antibody
Bevacizumab
LC-MS
MS
Surrogate peptide
Pharmacokinetics
Serum
Perfluoro-tert-butyl Group-Derived Capmatinib: Synthesis, Biological Evaluation and Its Application in F-19 Magnetic Resonance Imaging
期刊论文
OAI收割
CHEMBIOCHEM, 2023, 页码: 9
作者:
Zhang, Xinnan
;
Wang, Luting
;
Huang, Ruimin
;
Wang, Jingbo
;
Yan, Qifan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
F-19 MRI
Capmatinib derivatives
Targeted imaging
Fluorinated derivatization
Bioimaging
Efficacy of Near-Infrared Fluorescence Video-Assisted Thoracoscopic Surgery for Small Pulmonary Nodule Resection with Indocyanine Green Inhalation: A Randomized Clinical Trial
期刊论文
OAI收割
ANNALS OF SURGICAL ONCOLOGY, 2023, 页码: 11
作者:
Wang, Kun
;
Huang, Weiyuan
;
Chen, Xianshan
;
Li, Gao
;
Li, Na
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/11/17
SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 13
作者:
Zhou, Ji
;
Zhang, Xu-Chao
;
Xue, Shan
;
Dai, Mengdi
;
Wang, Yueliang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead
期刊论文
OAI收割
GENES & DISEASES, 2023, 卷号: 10, 期号: 2, 页码: 403-414
作者:
Li, Hui-yu
;
Qi, Wei-liang
;
Wang, Yu-xiang
;
Meng, Ling-hua
  |  
收藏
  |  
浏览/下载:117/0
  |  
提交时间:2023/10/17
Biomarkers
Covalent KRasG12Cinhibitors
Drug resistance
Human cancers
KRASG12Cmutation
Novel HER2-Targeted Peptide for NIR-II Imaging of Tumor
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2023, 卷号: 20, 期号: 2, 页码: 1394-1403
作者:
Cao, Rui
;
Li, Renda
;
Shi, Hui
;
Liu, Hongguang
;
Cheng, Zhen
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
NIR-II
peptide
HER2
tumor
optical imaging