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Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共305条，第1-10条 帮助

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Structure-Activity Relationships of 2-(Arylthio)benzoic Acid FTO Inhibitors 期刊论文  OAI收割
ISRAEL JOURNAL OF CHEMISTRY, 2024, 页码: 13
作者:  Yan, Chao;  Zhang, Qian;  Xiao, Pan;  Xie, Xinyun;  Li, Ming
  |  收藏  |  浏览/下载：26/0  |  提交时间：2024/03/25
Discovery of GPX4 inhibitors through FP-based high-throughput screening 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14
作者:  Cao, Yu;  Wu, Bin;  Xu, Ying;  Wang, Mingchen;  Wu, Xinyu
  |  收藏  |  浏览/下载：21/0  |  提交时间：2024/02/27
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:  Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun
  |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文  OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia
  |  收藏  |  浏览/下载：13/0  |  提交时间：2024/04/07
Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:  Dong, Sanfeng;  Hu, Ke;  Shi, Yulong;  Wang, Guanli;  Yu, Dandan
  |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/19
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua
  |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/19
Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study 期刊论文  OAI收割
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12
作者:  Zhao, Tian-Tian;  Hu, Hao-Jie;  Gao, Li-Xin;  Zhou, Yu-Bo;  Zhu, Yun-Long
  |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17
Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L 期刊论文  OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28
作者:  Li, Xin;  Wu, Xiaowei;  Nie, Shenyou;  Zhao, Jidong;  Yao, Yuan
  |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/19
Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 10
作者:  Li, Peizhuo;  Tian, Yucheng;  Shang, Qinghong;  Tang, Cailing;  Hou, Zeng
  |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17
Structural insights into the interaction of three Y- shaped ligands with PI3Kα 期刊论文  OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 34, 页码: 9
作者:  Zhou, Qingtong;  Liu, Xiao;  Neri, Dario;  Li, Wenxin;  Favalli, Nicholas
  |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08