中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G
s
proteins
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 13
作者:
Cong, Zhaotong
;
Zhao, Fenghui
;
Li, Yang
;
Luo, Gan
;
Mai, Yiting
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/03/13
Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
;
Chen, Xiaochen
;
Han, Li
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis
Application of ensemble learning for predicting GABA
A
receptor agonists
期刊论文
OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2024, 卷号: 169, 页码: 13
作者:
Xiao, Fu
;
Ding, Xiaoyu
;
Shi, Yan
;
Wang, Dingyan
;
Wang, Yitian
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/25
GABA(A )receptor
Benzodiazepine
Agonist
Machine learning
Classification
Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 10
作者:
Li, Peizhuo
;
Tian, Yucheng
;
Shang, Qinghong
;
Tang, Cailing
;
Hou, Zeng
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
NPAS3
Covalent inhibitor
Protein -protein interaction
5-nitrothiazole warhead
Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 14
作者:
Li, Cuixia
;
Wu, Yiran
;
Wang, Wenli
;
Xu, Lu
;
Zhou, Yan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes
期刊论文
OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 3, 页码: 9
作者:
Sun, Zengchao
;
Wang, Lu
;
Li, Lingyun
;
Sun, Yili
;
Zhang, Daizhou
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
SARS-CoV-2 virus
Receptor -binding domain
Nanobody
Crystal structure
Conservative binding epitope
Bi-paratopic nanobodies
Structural and mechanistic insights provided by single particle cryo-EM analysis of phosphoinositide 3-kinase (PI3Ka)
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023, 卷号: 1878, 期号: 5, 页码: 6
作者:
Vogt, Peter K.
;
Hart, Jonathan R.
;
Yang, Su
;
Zhou, Qingtong
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/10/17
Phosphoinositide 3-kinase
BYL-719
Nanobody
CXMS
Mutants
Zebrafish (Danio rerio) TR beta- and TTR-based electrochemical biosensors: Construction and application for the evaluation of thyroid-disrupting activity of bisphenols
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2023, 卷号: 330, 页码: 9
作者:
Li, Yuejiao
;
Zhang, Zhenzhong
;
Wang, Jun
;
Shan, Yeqi
;
Tian, Hua
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/07
Thyroid-disrupting chemicals
Thyroid hormone receptor beta
Transthyretin
In vitro screening Assay
Electrochemical biosensor
A Mannose Receptor from Litopenaeus vannamei Involved in Innate Immunity by Pathogen Recognition and Inflammation Regulation
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 13, 页码: 19
作者:
Guo, Na
;
Liu, Yuan
;
Hao, Qiang
;
Sun, Mingzhe
;
Li, Fuhua
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/13
mannose receptor
Litopenaeus vannamei
pathogen recognition
inflammation
ROS
Sensitivity-enhanced nanoplasmonic biosensor using direct immobilization of two engineered nanobodies for SARS-CoV-2 spike receptor-binding domain detection
期刊论文
OAI收割
SENSORS AND ACTUATORS B-CHEMICAL, 2023, 卷号: 383, 页码: 133575
作者:
Ma, Zhengtai
;
Sun, Zengchao
;
Lv, Xiaoqing
;
Chen, Hongda
;
Geng, Yong
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
Nanoplasmonics
Biosensor
COVID-19
Nanobody
Immobilization
High -throughput