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• 2021 [32]
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浏览/检索结果: 共474条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16 作者:  Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/25 Inhibitor  Cancer  Threonine tyrosine kinase (TTK)  Covalent   Design, Synthesis, and Anti-tuberculosis Activity of Streptomycin Derivatives 期刊论文  OAI收割 LETTERS IN DRUG DESIGN & DISCOVERY, 2024, 卷号: 21, 期号: 4, 页码: 738-748 作者:  Zhang, Yinyong;  Zhao, Wenhao;  Yang, Yushe;  Zhou, Xianli;  Guo, Bin   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/06 Multidrug-resistant  hydrazine  hydrazide  sulfonyl hydrazide  siderophore  synthesis  anti-tuberculosis activity   Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/02/19 Advances in biosynthesis of peptide drugs: Technology and industrialization 期刊论文  OAI收割 BIOTECHNOLOGY JOURNAL, 2023, 页码: 13 作者:  Wang, Jing;  Chen, Long;  Qin, Song;  Xie, Mingyuan;  Luo, Shi-Zhong   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/01/26 biosynthesis technology  industrialization  peptide drugs  peptide synthesis   Design, synthesis of auristatins-glucuronide conjugates targeting the β-glucuronidase in tumor microenvironment 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 5 作者:  Wang, Yujie;  Xu, Keshi;  Liu, Hongchun;  Zhang, Wei;  Hu, Chun   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/19 Auristatin E  beta-Glucuronidase  Antiproliferation  Tumor microenvironment   Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9 作者:  Lu, Shiwei;  Zhang, Feng;  Gong, Jiahao;  Huang, Jian;  Zhu, Guanghao   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 Cytochrome P450 3A4 (CYP3A4)  Inhibitors  Isoquinoline chalcones  Orally active   Design, synthesis, and biological evaluation of novel spirocyclic compounds as potential anti-glioblastoma agents 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 22 作者:  Zhu, Heping;  Song, Xiaomin;  Pan, Yihui;  Li, Ming;  Chen, Liang   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Glioblastoma  Spirocyclic compounds  Drug design  Antiproliferation   Perfluoro-tert-butyl Group-Derived Capmatinib: Synthesis, Biological Evaluation and Its Application in F-19 Magnetic Resonance Imaging 期刊论文  OAI收割 CHEMBIOCHEM, 2023, 页码: 9 作者:  Zhang, Xinnan;  Wang, Luting;  Huang, Ruimin;  Wang, Jingbo;  Yan, Qifan   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 F-19 MRI  Capmatinib derivatives  Targeted imaging  Fluorinated derivatization  Bioimaging   Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16 作者:  Chen, Yun;  Ning, Yi;  Chen, Zhiwei;  Xue, Yaping;  Wu, Qingyun   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Apoptosis  Diffuse large B-Cell lymphoma  Interleukin-1 receptor associated kinase 4  Structure-based drug design  2  3-Dihydrobenzofuran   Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 14, 期号: 8, 页码: 1073-1078 作者:  Seydimemet, Mengnisa;  Yang, Yixuan;  Lv, Yuhan;  Liu, Jiaxiang;  Yan, Ziqin   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 DNA-encoded library technology  Pyrimidine-focusedDNA-encodedlibrary  BRD4  Affinity screening  Inhibitor