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浏览/检索结果: 共274条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15 作者:  Yan, Xue;  Zhang, Chun;  Gao, Li-Xin;  Liu, Min -Min;  Yang, Yu-Ting   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 Imidazo[124] triazole derivatives  Fluorescence property  SHP1  Bioactivity  Cellular imaging   JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文  OAI收割 CANCER LETTERS, 2024, 卷号: 582, 页码: 15 作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/04/07 Acquired resistance  Cancer  NSCLC  JC-010a  SHP2   Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183 作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167 作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies 期刊论文  OAI收割 CELL, 2024, 卷号: 187, 期号: 1, 页码: 49 作者:  Liu, Qian;  Zhang, Jing;  Guo, Chenchen;  Wang, Mengcheng;  Wang, Chenfei   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/02/27 Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis 期刊论文  OAI收割 PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12 作者:  Tang, Shuai;  Duan, Yichen;  Yuan, Tao;  Hu, Yutinh;  Yuan, Liang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/11 KRAS  Pancreatic ductal adenocarcinoma  MAPK pathway  Tetrandrine  TRAIL  Death receptors   Chemical Inhibitors Targeting the Oncogenic m6A Modifying Proteins 期刊论文  OAI收割 ACCOUNTS OF CHEMICAL RESEARCH, 2023, 卷号: 56, 期号: 21, 页码: 3010-3022 作者:  Huang, Yue;  Xia, Wenyang;  Dong, Ze;  Yang, Cai-Guang   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/11 Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14 作者:  Xu, Zhuo;  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Zhu, Mengying   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Otilonium Bromide  Deubiquitinase  USP28  Selective inhibitor   Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612 作者:  Wang, Xiaomin;  Xu, Jun;  Sun, Yiming   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 HDAC inhibitors  Drug resistance  Histone methylation  Histone acetylation  Epigenetic interplay  Hedgehog pathway  ZIC1  LIFR  Combination therapy  Breast cancer   Elevated Nuclear PHGDH Synergistically Functions with cMyc to Reshape the Immune Microenvironment of Liver Cancer 期刊论文  OAI收割 ADVANCED SCIENCE, 2023, 卷号: 10, 期号: 17 作者:  Zhu, Hongwen;  Yu, Hua;  Zhou, Hu;  Zhu, Wencheng;  Wang, Xiongjun   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 cMyc  CXCL1  IL8  liver cancer  neutrophil  nuclear PHGDH