中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [16]
合肥物质科学研究院 [4]
海洋研究所 [3]
过程工程研究所 [2]
力学研究所 [1]
生态环境研究中心 [1]
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OAI收割 [29]
内容类型
期刊论文 [29]
发表日期
2022 [29]
学科主题
Biotechnol... [1]
Multidisci... [1]
Plant Scie... [1]
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浏览/检索结果:
共29条,第1-10条
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发表日期:2022
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Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15
作者:
Zhan, Zhengsheng
;
Ji, Yinchun
;
Su, Haixia
;
Fang, Chen
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/04/10
A SARS-CoV-2 vaccine based on conjugation of SARS-CoV-2 RBD with IC28 peptide and mannan
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 222, 页码: 661-670
作者:
He, Yunxia
;
Yu, Weili
;
Shen, Lijuan
;
Yan, Wenying
;
Xiao, Lucheng
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/02/24
SARS-CoV-2
RBD
Adjuvant
Targeting PI3K alpha overcomes resistance to KRas(G12C) inhibitors mediated by activation of EGFR and/or IGF1R
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:
Qi, Wei-liang
;
Li, Hui-yu
;
Wang, Yi
;
Xu, Lan
;
Deng, Jie-ting
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
AMG510
KRas(G12C)
PI3K
drug resistance
combination therapy
Dynamic cellular and molecular characteristics of spermatogenesis in the viviparous marine teleost Sebastes schlegelii
期刊论文
OAI收割
BIOLOGY OF REPRODUCTION, 2022, 页码: 15
作者:
Wang, Xueying
;
Liu, Qinghua
;
Li, Jun
;
Zhou, Li
;
Wang, Tao
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/02/01
Sebastes schlegelii
internal fertilization
spermatogenesis
spermiogenesis
single-cell RNA-seq
Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3K alpha
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 46, 页码: 11
作者:
Liu, Xiao
;
Zhou, Qingtong
;
Hart, Jonathan R.
;
Xu, Yingna
;
Yang, Su
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/10/17
phosphoinositide 3-kinase (PI3K)
mass spectrometry
mutants
Pulmonary Salivary Gland Tumor, Mucoepidermoid Carcinoma: A Literature Review
期刊论文
OAI收割
JOURNAL OF ONCOLOGY, 2022, 卷号: 2022
作者:
Hu, Shumin
;
Gong, Jiali
;
Zhu, Xiu
;
Lu, Hongyang
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/23
Smart drug delivery systems for precise cancer therapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4098-4121
作者:
Wang, Xiaoyou
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/04/10
Pharmaceutics
Smart drug delivery system
Stimuli-responsive
Receptor-ligand-based delivery
Nano-drug delivery systems
Precise therapy
Toxicity
Cancer
Whole-transcriptome sequencing data reveals a disparate cognitive and immune signature in COVID-19 patients with and without dementia
期刊论文
OAI收割
JOURNAL OF MEDICAL VIROLOGY, 2022, 页码: 10
作者:
Yang, Jue
;
Song, Hui
;
Hao, Xiaojiang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/12/13
Alzheimer's disease
COVID-19
dementia
immune response
SARS-CoV-2
Design, synthesis and evaluation of the Brigatinib analogues as potent inhibitors against tertiary EGFR mutants (EGFR(del19/T790M/C797S) and EGFR(L858R/T790M/C797S))
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 72, 页码: 11
作者:
Fang, Haotian
;
Wu, Yingming
;
Xiao, Qitao
;
He, Dongbo
;
Zhou, Tongrui
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/08/16
Non-small cell lung cancer
EGFR
Triple mutations
C797S
EGFR-TKIs
Key Considerations in Targeted Protein Degradation Drug Discovery and Development
期刊论文
OAI收割
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:
Qin, Liena
;
Dai, Han
;
Wang, Junfeng
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/12/23
targeted protein degradation
PROTAC
molecular glue
chemically induced proximity
drug discovery and development