机构

• 上海药物研究所 [32]

采集方式

• OAI收割 [32]

内容类型

• 期刊论文 [32]

发表日期

• 2023 [8]
• 2022 [8]
• 2021 [7]
• 2020 [9]

学科主题

筛选

浏览/检索结果: 共32条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 Sensitivity-enhanced nanoplasmonic biosensor using direct immobilization of two engineered nanobodies for SARS-CoV-2 spike receptor-binding domain detection 期刊论文  OAI收割 SENSORS AND ACTUATORS B-CHEMICAL, 2023, 卷号: 383, 页码: 133575 作者:  Ma, Zhengtai;  Sun, Zengchao;  Lv, Xiaoqing;  Chen, Hongda;  Geng, Yong   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 Nanoplasmonics  Biosensor  COVID-19  Nanobody  Immobilization  High -throughput   Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2 期刊论文  OAI收割 European journal of medicinal chemistry, 2023, 卷号: 249, 页码: 115129 作者:  Ren, Pengxuan;  Yu, Changyue;  Zhang, Ruxue   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/26 Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 18, 页码: 11 作者:  Xu, Haiyu;  Li, Shufen;  Liu, Jiayuan;  Cheng, Jinlong;  Kang, Liping   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/10/17 COVID-19  traditional Chinese medicine  TCMT-NDRD  antivirus  anti-inflammation   Discovery of Polyphenolic Natural Products as SARS-CoV-2 Mpro Inhibitors for COVID-19 期刊论文  OAI收割 PHARMACEUTICALS, 2023, 卷号: 16, 期号: 2, 页码: 190 作者:  Kruger, Nadine;  Kronenberger, Thales;  Xie, Hang;  Rocha, Cheila;  Pohlmann, Stefan   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/03/27 antivirals  coronavirus  COVID-19  covalent drugs  dynamic light scattering  inhibitors  main protease  natural products   Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 226, 页码: 780-792 作者:  Xiang, Yusen;  Zhai, Guanglei;  Li, Yaozong;  Wang, Mengge;  Chen, Xixiang   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/04/10 SARS-CoV-2  S-RBD  Ginkgolic acid   Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 11 作者:  Wang, Ruyu;  Zhai, Guanglei;  Zhu, Guanghao;  Wang, Mengge;  Gong, Xiaoyi   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/04/10 SARS-CoV-23CLpro  Thonzonium bromide  Mechanism of action  Broad-spectrum inhibitor   Whole-transcriptome sequencing data reveals a disparate cognitive and immune signature in COVID-19 patients with and without dementia 期刊论文  OAI收割 JOURNAL OF MEDICAL VIROLOGY, 2022, 页码: 10 作者:  Yang, Jue;  Song, Hui;  Hao, Xiaojiang   |  收藏  |  浏览/下载：32/0  |  提交时间：2022/12/13 Alzheimer's disease  COVID-19  dementia  immune response  SARS-CoV-2   New laboratory evidence for the association between endothelial dysfunction and COVID-19 disease progression 期刊论文  OAI收割 JOURNAL OF MEDICAL VIROLOGY, 2022, 页码: 9 作者:  Liu, Nan;  Long, Hui;  Sun, Jianhua;  Li, Huan;  He, Yunting   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/06/15 COVID-19  endothelial dysfunction  laboratory evidence  prognosis