中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [99]
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OAI收割 [99]
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期刊论文 [98]
会议论文 [1]
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2024 [1]
2023 [1]
2022 [7]
2021 [4]
2020 [4]
2019 [5]
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Toxicology [1]
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Selective FRET nano probe based on carbon dots and naphthalimide-isatin for the ratiometric detection of peroxynitrite in drug-induced liver injury
期刊论文
OAI收割
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 2, 页码: 757-764
作者:
Wu, Yueci
;
Sun, Lu-Lu
;
Han, Hai-Hao
;
He, Xiao-Peng
;
Cao, Weiguo
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Inhibition of estrogen sulfation by Xian-Ling-Gu-Bao capsule
期刊论文
OAI收割
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2023, 卷号: 225, 页码: 12
作者:
He, Liangliang
;
Chen, Chanjuan
;
Duan, Shuyi
;
Li, Yang
;
Li, Chuan
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/11/11
Xian-Ling-Gu-Bao capsule
Estrogens
Sulfotransferase enzymes
Inhibitory effects
Molecular docking
Identification of naturally occurring inhibitors in Xian-Ling-Gu-Bao capsule against the glucuronidation of estrogens
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 17
作者:
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/04/10
Xian-Ling-Gu-Bao capsule
estrogens
glucuronidation
inhibitory effects
UDP-glucuronosyltransferase
Nrf2-mediated liver protection by 18 beta-glycyrrhetinic acid against pyrrolizidine alkaloid-induced toxicity through PI3K/Akt/GSK3 beta pathway
期刊论文
OAI收割
PHYTOMEDICINE, 2022, 卷号: 102, 页码: 12
作者:
Wang, Zhangting
;
Ma, Jiang
;
He, Yisheng
;
Miu, Kai-Kei
;
Yao, Sheng
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/08/30
Pyrrolizidine alkaloids
Herb-induced liver injury
18 beta-glycyrrhetinic acid
Liquorice
Nuclear factor erythroid-2-related factor 2
PI3K/Akt/GSK3 beta
FEK self-assembled peptide hydrogels facilitate primary hepatocytes culture and pharmacokinetics screening
期刊论文
OAI收割
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2022, 页码: 13
作者:
He, Ting
;
Qiao, Shida
;
Ma, Chen
;
Peng, Zhaoliang
;
Wu, Zhitao
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/06/15
biliary excretion index
FEFEFKFK self-assembling peptide hydrogel
metabolic enzymes
rat primary hepatocytes
sandwich culture
transporters
Liquorice Extract and 18 beta-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic Activation
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 14
作者:
Wang, Zhangting
;
Ma, Jiang
;
Yao, Sheng
;
He, Yisheng
;
Miu, Kai-Kei
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/06/15
18 beta-glycyrrhetinic acid
pyrrolizidine alkaloid
cytochrome P450
metabolic activation
competitive inhibition
Farnesoid X receptor (FXR) agonists induce hepatocellular apoptosis and impair hepatic functions via FXR/SHP pathway
期刊论文
OAI收割
ARCHIVES OF TOXICOLOGY, 2022, 页码: 15
作者:
Zhang, Tianwei
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/06/15
FXR agonist
Hepatotoxicity
Farnesoid X receptor
Obeticholic acid
Px-102
Apoptosis
Kupffer cells play a crucial role in monocrotaline-induced liver injury by producing TNF-alpha
期刊论文
OAI收割
TOXICOLOGY, 2022, 卷号: 468, 页码: 9
作者:
Cao, Yuhan
;
Liu, Meng
;
Wu, Shouyan
;
Xu, Junjiu
;
Wang, Wenjie
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/06/15
Monocrotaline
Kupffer cells
Necrosis
Hepatotoxicity
Dietary alcohol exacerbates the hepatotoxicity induced by pyrrolizidine alkaloids: Hazard from food contamination
期刊论文
OAI收割
JOURNAL OF HAZARDOUS MATERIALS, 2022, 卷号: 424, 页码: 12
作者:
He, Yisheng
;
Long, Yun
;
Zhang, Chunyuan
;
Ma, Jiang
;
Ke, Changqiang
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/06/15
food contamination
pyrrolizidine alkaloids
alcohol
dietary exposure
mead
Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
OAI收割
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction