中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [150]
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OAI收割 [150]
内容类型
期刊论文 [148]
会议论文 [2]
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2023 [8]
2022 [7]
2021 [5]
2020 [9]
2019 [3]
2018 [11]
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专题:上海药物研究所
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Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Hao, Bing-bing
;
Ma, Ke
;
Xu, Jun-yu
;
Fan, Ru-feng
;
Zhao, Wen-si
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/25
solid tumor
histone deacetylase inhibitor
vorinostat (SAHA)
drug resistance
proteomics
Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF)
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12
作者:
Wu, Xinyu
;
Wang, Mingchen
;
Cao, Yu
;
Xu, Ying
;
Yang, Ziqun
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/02/27
O-GlcNAcylation
O-GlcNAc transferase
High-throughput screening
Inhibitor
Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in cancer
期刊论文
OAI收割
CANCER CELL, 2023, 卷号: 41, 期号: 7, 页码: 1345-+
作者:
Wang, Hanling
;
Li, Ni
;
Liu, Qiuli
;
Guo, Jiacheng
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
"Two Birds One Stone" Strategy for the Site-Specific Analysis of Core Fucosylation and O-GlcNAcylation
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 页码: 9
作者:
Luo, Yawen
;
Wang, Yuqiu
;
Tian, Yinping
;
Zhou, Hu
;
Wen, Liuqing
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Ratiometric sensing of beta-galactosidase based on excited-state intramolecular proton transfer (ESIPT) and solid-state luminescence enhancement
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 10, 期号: 12, 页码: 2913-2917
作者:
Tian Jr, He
;
Lin, Wei
;
Hu, Xi-Le
;
Wang, Jing-Bo
;
Zhang, Min-Yu
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 378, 页码: 11
作者:
Yang, Yun
;
Xiong, Yuan
;
Zhu, Guanghao
;
Sun, Mengru
;
Zou, Kun
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Human carboxylesterase 2 (hCES2A)
Berberine analogues
Structure -activity relationships (SAR)
Inhibition kinetics
Selectivity
Cell penetrating peptides: Highlighting points in cancer therapy
期刊论文
OAI收割
DRUG DEVELOPMENT RESEARCH, 2023, 页码: 35
作者:
Asrorov, Akmal M.
;
Wang, Huiyuan
;
Zhang, Meng
;
Wang, Yonghui
;
He, Yang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/10/17
amphipathic peptides
cationic peptides
cell-penetrating peptides
cyclic peptides
hydrophobic peptides
polyarginines
A hydrogen-deuterium exchange mass spectrometry-based protocol for protein-small molecule interaction analysis
期刊论文
OAI收割
Biophysics reports, 2023, 卷号: 9, 期号: 2, 页码: 99-111
作者:
Meng, Qian
;
Song, Yuan-Li
;
Zhou, Chen
;
He, Han
;
Zhang, Naixia
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/26
Development and validation of a LC-MS/MS method for quantitation of recombinant human growth hormone in rat plasma and application to a pharmacokinetic study
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 224, 页码: 9
作者:
Huang, Wen-si
;
Yu, Jing-hua
;
Diao, Xing-xing
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
Recombinant human growth hormone (rhGH)
Somatotropin
Method validation
LC-MS
MS
Pharmacokinetics
Validated quantitative P-31 NMR spectroscopy for positional isomeric impurity determination in L-alpha-glycerylphosphorylcholine (L-alpha-GPC)
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2022, 卷号: 221, 页码: 5
作者:
Sun, Ling
;
Fan, Yujuan
;
Wang, Qiaoqiao
;
Xiang, Lili
;
Han, Haiyun
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
P-31 NMR spectroscopy
Positional isomers
Impurity
L-alpha-glycerylphosphorylcholine (L-alpha-GPC)
Method validation
Quality control