机构

• 上海药物研究所 [31]

采集方式

• OAI收割 [31]

内容类型

• 期刊论文 [31]

发表日期

• 2023 [2]
• 2021 [2]
• 2020 [1]
• 2019 [4]
• 2017 [1]
• 2016 [2]
• 更多

学科主题

• Pharmacolo... [1]

筛选

浏览/检索结果: 共31条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Exploration of novel four-membered-heterocycle constructed peptidyl proteasome inhibitors with improved metabolic stability for cancer treatment 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 138, 页码: 22 作者:  Wang, Hanlin;  Wu, Zhaoxiao;  Cao, Yu;  Gao, Lixin;  Shao, Jiaan   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/10/17 Metabolic stability  Four-membered heterocycles  Proteasome inhibitors  Multiple myeloma   Privileged heterocycles for DNA-encoded library design and hit-to-lead optimization 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 26 作者:  Wen, Xin;  Wu, Xinyuan;  Jin, Rui;  Lu, Xiaojie   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/04/10 DNA Encoded library  Drug discovery  Heterocycles  Hit identification  Lead generation   Synthesis and Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitory Activity Evaluation of Novel N-Acylhydrazone Derivatives Containing Carbazole and Aromatic Ring/Aromatic Fused Heterocycle 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 9, 页码: 3593-3607 作者:  Li Yingjun;  Lin Ledi;  Liu Jihong;  Gao Lixin;  Sheng Li   |  收藏  |  浏览/下载：43/0  |  提交时间：2021/12/01 PTP1B inhibitor  carbazole  N-actylhydrazone  synthesis  molecular docking   DNA-encoded C-H functionality via photoredox-mediated hydrogen atom transformation catalysis 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 42, 页码: 4 作者:  Shan, Jinming;  Ling, Xing;  Liu, JiaXiang;  Wang, Xuan;  Lu, Xiaojie   |  收藏  |  浏览/下载：32/0  |  提交时间：2021/08/17 Photoredox  Hydrogen atom transfer  N-Boc saturated heterocycle  DNA Encoded Library (DEL)   NaH Promoted One-Pot Tandem Reactions of 3-(1-Alkynyl) Chromones to Form 2-Nitrogen-Substituted Xanthones 期刊论文  OAI收割 ACS OMEGA, 2020, 卷号: 5, 期号: 22, 页码: 13454-13461 作者:  Duan, Wen-Di;  Zhang, Yu-Fang;  Hu, Youhong   |  收藏  |  浏览/下载：59/0  |  提交时间：2020/12/24 Rh(III)-Catalyzed C-H Bond Activation for the Construction of Heterocycles with sp(3)-Carbon Centers 期刊论文  OAI收割 CATALYSTS, 2019, 卷号: 9, 期号: 10, 页码: 29 作者:  Wang, Run;  Xie, Xiong;  Liu, Hong;  Zhou, Yu   |  收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01 C-H bond activation  Rhodium(III)-based catalysts  heterocycle with sp(3) carbon centers  chirality   Green and Facile Assembly of Diverse Fused N-Heterocycles Using Gold-Catalyzed Cascade Reactions in Water 期刊论文  OAI收割 MOLECULES, 2019, 卷号: 24, 期号: 5, 页码: 30 作者:  Jia, Xiuwen;  Li, Pinyi;  Liu, Xiaoyan;  Lin, Jiafu;  Chu, Yiwen   |  收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01 amine nucleophiles  alkynoic acids  cascade reaction  gold catalysis  fused N-heterocycles   One-Pot NBS-Promoted Synthesis of Imidazoles and Thiazoles from Ethylarenes in Water 期刊论文  OAI收割 MOLECULES, 2019, 卷号: 24, 期号: 5, 页码: 13 作者:  Chen, Liang;  Zhu, Huajian;  Wang, Jiang;  Liu, Hong   |  收藏  |  浏览/下载：10/0  |  提交时间：2020/07/01 NBS  nitrogen-containing heterocycle  water  one-pot   coppercatalyzedselectivechtrifluoromethylationofacrylamideswithtmscf3 期刊论文  OAI收割 chinesechemicalletters, 2019, 卷号: 30, 期号: 5, 页码: 969 作者:  Sun Shangzheng;  Xu Hui;  Dai Huixiong   |  收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01 C–H trifluoromethylation  Copper  Acrylamides  Heterocycle   LLDT-288, a novel triptolide analogue exhibits potent antitumor activity in vitro and in vivo 期刊论文  OAI收割 BIOMEDICINE & PHARMACOTHERAPY, 2017, 卷号: 93, 页码: 1004-1009 作者:  Xu, Hongtao;  Fan, Xiaoting;  Zhang, Guanjun;  Liu, Xiaoyu;  Li, Zhihong   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 Triptolide  Natural products  Drug-resistance  CYP