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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [417]
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OAI收割 [417]
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期刊论文 [409]
会议论文 [8]
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2024 [9]
2023 [40]
2022 [36]
2021 [38]
2020 [34]
2019 [21]
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Chemistry [11]
Pharmacolo... [9]
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共417条,第1-10条
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In vitro inhibition of six active sesquiterpenoids in zedoary turmeric oil on human liver cytochrome P450 enzymes
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 322, 页码: 10
作者:
Liu, Suyan
;
Zhao, Yong
;
Tang, Xuan
;
Yang, Junling
;
Pan, Chen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/02/27
Sesquiterpenoids
Inhibition
CYP450s
Drug-drug interactions
Mechanism
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
d
]pyrimidin-7(6
H
)-one" Scaffold for the Treatment of B Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:
Liang, Xuewu
;
Yu, Haolan
;
Liang, Renwen
;
Feng, Zhuanghui
;
Saidahmatov, Abdusaid
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/09
Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G
s
proteins
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 13
作者:
Cong, Zhaotong
;
Zhao, Fenghui
;
Li, Yang
;
Luo, Gan
;
Mai, Yiting
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/03/13
Regulating protein corona on nanovesicles by glycosylated polyhydroxy polymer modification for efficient drug delivery
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 20
作者:
Miao, Yunqiu
;
Li, Lijun
;
Wang, Ying
;
Wang, Jiangyue
;
Zhou, Yihan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/13
Metabolic regulation of homologous recombination repair by MRE11 lactylation
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 2, 页码: 40
作者:
Chen, Yuping
;
Wu, Jinhuan
;
Zhai, Linhui
;
Zhang, Tingting
;
Yin, Hui
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/04/09
Structure-based optimization of indoline-containing compounds as second generation inhibitors of NF-KB-inducing kinase (NIK)
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1295, 页码: 19
作者:
Cheng, Jing
;
Yan, Ziqin
;
Li, Xinzhi
;
Liu, Chen
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Kinase inhibitor
NIK
NF-KB2
Indoline
COT
Cytotoxicity
Multi-omics reveals the attenuation of metabolic cardiomyopathy in mice by alkaloids in extracts from
Clausena
lansium
(Lour.) via the transition of gastrointestinal microbiota to an alternative homeostasis
期刊论文
OAI收割
JOURNAL OF FUNCTIONAL FOODS, 2024, 卷号: 112, 页码: 15
作者:
Shu, Chi
;
Huang, Jian-yuan
;
Yang, Gui-yuan
;
Xing, Na
;
Zhao, Yong
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/02/27
Alkaloids
Duncaniella
Girinimbine
Norleucine
Metabolic disorders
Wampee
Design, Synthesis, and Anti-tuberculosis Activity of Streptomycin Derivatives
期刊论文
OAI收割
LETTERS IN DRUG DESIGN & DISCOVERY, 2024, 卷号: 21, 期号: 4, 页码: 738-748
作者:
Zhang, Yinyong
;
Zhao, Wenhao
;
Yang, Yushe
;
Zhou, Xianli
;
Guo, Bin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/03/06
Multidrug-resistant
hydrazine
hydrazide
sulfonyl hydrazide
siderophore
synthesis
anti-tuberculosis activity
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects