中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
采集方式
OAI收割 [10]
内容类型
期刊论文 [10]
发表日期
2019 [10]
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专题:上海药物研究所
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发表日期:2019
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Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:
Xiao, Li
;
Wang, Yujun
;
Zhang, Mumei
;
Wu, Weiwei
;
Kong, Linghui
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2020/07/01
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2019, 卷号: 11, 期号: 519, 页码: 12
作者:
Liao, Ping
;
Qiu, Yunguang
;
Mo, Yiqing
;
Fu, Jie
;
Song, Zhenpeng
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
Current trends in drug metabolism and pharmacokinetics
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1113-1144
作者:
Li, Yuhua
;
Meng, Qiang
;
Yang, Mengbi
;
Liu, Dongyang
;
Hou, Xiangyu
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
Pharmacokinetics
Drug metabolism
Drug-drug interactions
Modeling
Metabolizing enzymes
Transporters
Nuclear receptors
Noncoding RNAs
Proteomic analysis of male rat nucleus accumbens, dorsal hippocampus and amygdala on conditioned place aversion induced by morphine withdrawal
期刊论文
OAI收割
BEHAVIOURAL BRAIN RESEARCH, 2019, 卷号: 372, 页码: 8
作者:
Guo, Liu-bin
;
Yu, Chuan
;
Ling, Qing-lan
;
Fu, Yu
;
Wang, Yu-jun
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Morphine withdrawal
Aversive memories
Proteomics
Synaptic plasticity
Amygdala
Dorsal hippocampus
Safety, Efficacy, and Biomarker Analysis of Pyrotinib in Combination with Capecitabine in HER2-Positive Metastatic Breast Cancer Patients: A Phase I Clinical Trial
期刊论文
OAI收割
CLINICAL CANCER RESEARCH, 2019, 卷号: 25, 期号: 17, 页码: 5212-5220
作者:
Li, Qiao
;
Guan, Xiuwen
;
Chen, Shanshan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Hepatoprotective effects of a traditional Chinese medicine formula against carbon tetrachloride-induced hepatotoxicity in vivo and in vitro
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 117, 页码: 8
作者:
Ren, Xia
;
Xin, Lan-Ting
;
Zhang, Meng-Qi
;
Zhao, Qing
;
Yue, Shi-Yun
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Traditional Chinese medicine
Le-Cao-Shi formula
Acute liver injury
Hepatoprotective effect
High-throughput screen reveals sRNAs regulating crRNA biogenesis by targeting CRISPR leader to repress Rho termination
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 12
作者:
Lin, Ping
;
Pu, Qinqin
;
Wu, Qun
;
Zhou, Chuanmin
;
Wang, Biao
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 15
作者:
Jin, Nan
;
Bi, Aiwei
;
Lan, Xiaojing
;
Xu, Jun
;
Wang, Xiaomin
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Identification of Glutaminyl Cyclase isoenzyme isoQC as a regulator of SIRP alpha-CD47 axis
期刊论文
OAI收割
CELL RESEARCH, 2019, 卷号: 29, 期号: 6, 页码: 502-505
作者:
Wu, Zhiqiang
;
Weng, Linjun
;
Zhang, Tengbo
;
Tian, Hongling
;
Fang, Lan
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
currenttrendsindrugmetabolismandpharmacokinetics
期刊论文
OAI收割
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1113
作者:
Liu Dongyang
;
Hou Xiangyu
;
Tang Lan
;
Wang Xin
;
Lyu Yuanfeng
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
ARYL-HYDROCARBON RECEPTOR
BLOOD-BRAIN-BARRIER
ORGANIC ANION TRANSPORTERS
CHRONIC KIDNEY-DISEASE
PREGNANE-X-RECEPTOR
P-GLYCOPROTEIN
QUANTITATIVE PREDICTION
CYTOCHROME-P450 ENZYMES
DOWN-REGULATION
IN-VIVO
Pharmacokinetics
Drug metabolism
Drug-drug interactions
Modeling
Metabolizing enzymes
Transporters
Nuclear receptors
Noncoding RNAs