中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [136]
采集方式
OAI收割 [136]
内容类型
期刊论文 [136]
发表日期
2024 [2]
2023 [15]
2022 [20]
2021 [14]
2020 [5]
2019 [10]
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专题:上海药物研究所
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7-Dehydrocholesterol dictates ferroptosis sensitivity
期刊论文
OAI收割
NATURE, 2024, 卷号: 626, 期号: 7998, 页码: 29
作者:
Li, Yaxu
;
Ran, Qiao
;
Duan, Qiuhui
;
Jin, Jiali
;
Wang, Yanjin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/09
Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
;
Chen, Xiaochen
;
Han, Li
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis
The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus
期刊论文
OAI收割
VIRULENCE, 2023, 卷号: 14, 期号: 1, 页码: 2171641
作者:
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Staphylococcus aureus
Sortase A
protein phosphorylation
virulence
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
Preparation and characteristics of a thermosensitive
in
situ
gel loaded with chitosan nanoparticles for optimal ocular delivery of chloramphenicol
期刊论文
OAI收割
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2023, 卷号: 89, 页码: 12
作者:
Huang, Changying
;
Peng, Liyang
;
Xu, Xinqi
;
Lu, Yunshu
;
Wang, Xueting
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/01/16
In situ gels
Chloramphenicol
Nanoparticles
Drug release
Antimicrobial activity
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes
期刊论文
OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 3, 页码: 9
作者:
Sun, Zengchao
;
Wang, Lu
;
Li, Lingyun
;
Sun, Yili
;
Zhang, Daizhou
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
SARS-CoV-2 virus
Receptor -binding domain
Nanobody
Crystal structure
Conservative binding epitope
Bi-paratopic nanobodies
A procedure for producing an anti-AXL nanobody in E. coli
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106268
作者:
Lan, Zhongyun
;
Li, Lingyun
;
Sun, Yili
;
Meng, Xiangjing
;
Shi, Zhenzhong
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/27
AXL
Nanobody
Expression
Purification
The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 23
作者:
Wang, Xin
;
Lin, Di-Hang
;
Yan, Yue
;
Wang, An-Hui
;
Liao, Jiaoyang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
PIWI
piRNAs
PIWI-Ins
translational activation
spermatid development
male fertility
"Platelet-coated bullets" biomimetic nanoparticles to ameliorate experimental colitis by targeting endothelial cells
期刊论文
OAI收割
BIOMATERIALS ADVANCES, 2023, 卷号: 148, 页码: 13
作者:
Song, Yijie
;
He, Yihao
;
Rong, Lan
;
Wang, Zhicheng
;
Ma, Yueming
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
Inflammatory bowel disease
Patchouli alcohol
Platelet mimetic nanoparticles