机构

• 上海药物研究所 [86]

采集方式

• OAI收割 [86]

内容类型

• 期刊论文 [85]
• 会议论文 [1]

发表日期

• 2024 [3]
• 2023 [9]
• 2022 [9]
• 2021 [6]
• 2020 [7]
• 2019 [7]
• 更多

学科主题

筛选

浏览/检索结果: 共86条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183 作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies 期刊论文  OAI收割 CELL, 2024, 卷号: 187, 期号: 1, 页码: 49 作者:  Liu, Qian;  Zhang, Jing;  Guo, Chenchen;  Wang, Mengcheng;  Wang, Chenfei   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/02/27 Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis 期刊论文  OAI收割 CELL METABOLISM, 2023, 卷号: 35, 期号: 10, 页码: 1752-+ 作者:  Kuang, Junliang;  Wang, Jieyi;  Li, Yitao;  Li, Mengci;  Zhao, Mingliang   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/08 Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology 期刊论文  OAI收割 SCIENCE TRANSLATIONAL MEDICINE, 2023, 卷号: 15, 期号: 706, 页码: 15 作者:  Ji, Shuyi;  Feng, Li;  Fu, Zile;  Wu, Gaohua;  Wu, Yingcheng   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/10/17 SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 13 作者:  Zhou, Ji;  Zhang, Xu-Chao;  Xue, Shan;  Dai, Mengdi;  Wang, Yueliang   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2 期刊论文  OAI收割 Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 5, 页码: 2384-2391 作者:  Xu, Zhijian;  Shi, Danrong;  Han, Jianbao;  Ling, Yun;  Jiang, Xiangrui   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/03/27 Structural Optimization of Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3226-3249 作者:  Li, Chunpu;  Dai, Yang;  Kong, Xiangtai;  Wang, Bao;  Peng, Xia   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27 Selective Covalent Targeting of Pyruvate Kinase M2 Using Arsenous Warheads 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 4, 页码: 2608-2621 作者:  Wang, Jingyao;  Zhou, Shaoqing;  Cheng, Yan;  Cheng, Lin;  Qin, Ying   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/03/27