机构

• 上海药物研究所 [190]

采集方式

• OAI收割 [190]

内容类型

• 期刊论文 [181]
• 会议论文 [8]
• 专利 [1]

发表日期

• 2023 [17]
• 2022 [5]
• 2021 [8]
• 2020 [9]
• 2019 [10]
• 2018 [10]
• 更多

学科主题

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浏览/检索结果: 共190条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15 作者:  Yan, Xue;  Zhang, Chun;  Gao, Li-Xin;  Liu, Min -Min;  Yang, Yu-Ting   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 Imidazo[124] triazole derivatives  Fluorescence property  SHP1  Bioactivity  Cellular imaging   Reversible SAHH inhibitor ameliorates MIA-induced osteoarthritis of rats through suppressing MEK/ERK pathway 期刊论文  OAI收割 BIOMEDICINE & PHARMACOTHERAPY, 2024, 卷号: 170, 页码: 6 作者:  Fan, Shu-Hui;  Chang, Yuan;  Xiong, Xiao-Yu;  Xiang, Mai;  Yuan, Wen-Long   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 DZ2002  Osteoarthritis  Osteoclast  Bone resorption   Safety, tolerability and pharmacokinetics of forsythin in healthy subjects: a double-blinded, placebo-controlled single-dose and multiple-dose escalation and food effect study 期刊论文  OAI收割 ANNALS OF MEDICINE, 2023, 卷号: 55, 期号: 2, 页码: 9 作者:  Li, Cuiyun;  Wu, Min;  Zhang, Hong;  Zhu, Xiaoxue;  Fu, Li   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/01/16 Forsythin  pharmacokinetics  safety  tolerability  food effect   Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis 期刊论文  OAI收割 PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12 作者:  Tang, Shuai;  Duan, Yichen;  Yuan, Tao;  Hu, Yutinh;  Yuan, Liang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/11 KRAS  Pancreatic ductal adenocarcinoma  MAPK pathway  Tetrandrine  TRAIL  Death receptors   Natural product P57 induces hypothermia through targeting pyridoxal kinase 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Wang, Ruina;  Xiao, Lei;  Pan, Jianbo;  Bao, Guangsen;  Zhu, Yunmei   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/02/19 Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13 作者:  Yang, Hanxi;  You, Mengyuan;  Shu, Xiaoyang;  Zhen, Jingyao;  Zhu, Mengwei   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/10/17 Peptidomimetics  Benzothiazolyl ketone  3CLpro inhibitor  Pharmacokinetic properties  SARS-CoV-2   Exploration of novel four-membered-heterocycle constructed peptidyl proteasome inhibitors with improved metabolic stability for cancer treatment 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 138, 页码: 22 作者:  Wang, Hanlin;  Wu, Zhaoxiao;  Cao, Yu;  Gao, Lixin;  Shao, Jiaan   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/10/17 Metabolic stability  Four-membered heterocycles  Proteasome inhibitors  Multiple myeloma   DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3KAkt-NF-kappa B pathway 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14 作者:  Wu, Chun-mei;  Mao, Jia-wen;  Zhu, Jin-zhi;  Xie, Can-can;  Yao, Jia-ying   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 dry eye disease  DZ2002  corneal angiogenesis  immunomodulatory function  NF-kappa B  ophthalmic therapy   Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11 作者:  Zhao, Yitian;  Zhang, Min;  Hou, Xudong;  Han, Jiaxin;  Qin, Xiaoya   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Salicylanilide  hPL inhibitor  Structure -activity relationship  Anti -obesity   Identification of XAF1 as an endogenous AKT inhibitor 期刊论文  OAI收割 CELL REPORTS, 2023, 卷号: 42, 期号: 7, 页码: 25 作者:  Chen, Min;  Wang, Kangjunjie;  Han, Ying;  Yan, Shukun;  Yuan, Huairui   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17