中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [84]
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OAI收割 [84]
内容类型
期刊论文 [82]
会议论文 [2]
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2024 [2]
2023 [3]
2022 [2]
2021 [16]
2020 [11]
2019 [6]
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专题:上海药物研究所
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Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
;
Chen, Xiaochen
;
Han, Li
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis
A NIR-II Photoacoustic/NIR-IIa Fluorescent Probe for Targeted Imaging of Glioma under NIR-II Excitation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 3, 页码: 1861-1871
作者:
Lyu, Shuxin
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/13
The new direction of drug development: Degradation of undruggable targets through targeting chimera technology
期刊论文
OAI收割
MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54
作者:
Liang, Xuewu
;
Ren, Hairu
;
Han, Fengyang
;
Liang, Renwen
;
Zhao, Jiayan
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/01/16
chimeric design
degradation System
PROTAC
targeted degradation technology
undruggable targets
Original Research Response to programmed cell death protein 1 antibody in patients with Epstein-Barr virus-associated intrahepatic cholangiocarcinoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF CANCER, 2023, 卷号: 194, 页码: 9
作者:
He, Wen-Zhuo
;
Huang, Yu-Hua
;
Hu, Wan-Ming
;
Wang, Fang
;
Xu, Yu-Xia
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/11
Epstein-Barr virus
Intrahepatic cholangiocarcinoma
Programmed cell death protein 1
Immunotherapy
Identification of lignans as ATP citrate lyase (ACLY) inhibitors from the roots of Pouzolzia zeylanica
期刊论文
OAI收割
NATURAL PRODUCT RESEARCH, 2023, 页码: 8
作者:
Li, Jin-Long
;
Jiang, Jia-Yi
;
Gu, Shan-Shan
;
Zhang, Lei
;
Sun, Yan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Pouzolzia zeylanica
lignans
ATP citrate lyase (ACLY) inhibitors
Overview of the preparation method, structure and function, and application of natural peptides and polypeptides
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2022, 卷号: 153, 页码: 7
作者:
Feng, Li
;
Wang, Yue
;
Yang, Jian
;
Sun, Yi-fan
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/09/30
Natural peptide and polypeptide
Preparation
Structure-activity relationship
Application
The p300 Inhibitor A-485 Exerts Antitumor Activity in Growth Hormone Pituitary Adenoma
期刊论文
OAI收割
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2022, 页码: 10
作者:
Ji, Chenxing
;
Xu, Wen
;
Ding, Hong
;
Chen, Zhengyuan
;
Shi, Chengzhang
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/06/15
p300
A-485
growth hormone pituitary adenoma
Sulfoximines Assisted Rh(III)-Catalyzed C-H Activation/Annulation Cascade to Synthesize Highly Fused Indeno-1,2-benzothiazines
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 21, 页码: 15217-15227
作者:
Li, Jian
;
Li, Hui
;
Fang, Daqing
;
Liu, Lingjun
;
Han, Xu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/04
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
;
Su, Mingbo
;
Lian, Fulin
;
Cong, Zhanqing
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:
Han, Xu
;
Song, Ning
;
Saidahmatov, Abdusaid
;
Wang, Peipei
;
Wang, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/12/16