中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [16]
自动化研究所 [4]
地质与地球物理研究所 [2]
心理研究所 [2]
海洋研究所 [2]
地理科学与资源研究所 [1]
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OAI收割 [30]
内容类型
期刊论文 [30]
发表日期
2023 [30]
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From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation
期刊论文
OAI收割
CELL CHEMICAL BIOLOGY, 2023, 卷号: 30, 期号: 11, 页码: 1421-+
作者:
Xiao, Yufeng
;
Hale, Seth
;
Awasthee, Nikee
;
Meng, Chengcheng
;
Zhang, Xuan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/16
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship
Natural ilmenite reference material for trace elemental in situ microanalysis
期刊论文
OAI收割
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY, 2023, 卷号: 209, 页码: 7
作者:
Luo, Yang
;
Wang, Jing
;
Xiao, Yan
;
Li, Wen-Jun
;
Wang, Shi-Ying
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/27
Ilmenite
Reference material
EMPA
LA-ICP-MS
Subband fusion of complex spectrogram for fake speech detection
期刊论文
OAI收割
SPEECH COMMUNICATION, 2023, 卷号: 155, 页码: 8
作者:
Fan, Cunhang
;
Xue, Jun
;
Dong, Shunbo
;
Ding, Mingming
;
Yi, Jiangyan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/26
Automatic speaker verification
Complex spectrogram
Fake speech detection
Phase information
Subband
A green approach to mica nanosheet production: Liquid-phase exfoliation in natural seawater
期刊论文
OAI收割
MATERIALS LETTERS, 2023, 卷号: 348, 页码: 4
作者:
Ding, Xiaoya
;
Wang, Yi
;
Wang, Jin
;
Zhang, Peng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/13
Structural
Nanoparticles
Microstructure
Appointed-Time Control for Flexible Hypersonic Vehicles with Conditional Disturbance Negation
期刊论文
OAI收割
IEEE TRANSACTIONS ON AEROSPACE AND ELECTRONIC SYSTEMS, 2023, 卷号: 59, 期号: 5, 页码: 6327-6345
作者:
Sun, Jinlin
;
Pu, Zhiqiang
;
Chang, Yafei
;
Ding, Shihong
;
Yi, Jianqiang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/02/22
Vehicle dynamics
Convergence
Control systems
Aerodynamics
Closed loop systems
Actuators
Mathematical models
Appointed-time control
conditional disturbance negation
hypersonic vehicle
input saturation
prescribed performance control
Hepatic glucuronyl C5-epimerase combats obesity by stabilising GDF15
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2023, 卷号: 79, 期号: 3, 页码: 14
作者:
He, Fei
;
Jiang, Haowen
;
Peng, Chang
;
Wang, Tingting
;
Xiao, Rongrong
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2023/10/17
Glucuronyl C5-epimerase
Growth differentiation factor-15
Obesity
Energy expenditure
Ubiquitination
Two-stage deep spectrum fusion for noise-robust end-to-end speech recognition
期刊论文
OAI收割
APPLIED ACOUSTICS, 2023, 卷号: 212, 页码: 10
作者:
Fan, Cunhang
;
Ding, Mingming
;
Yi, Jiangyan
;
Li, Jinpeng
;
Lv, Zhao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2023/11/16
Robust end-to-end ASR
Speech enhancement
Masking and mapping
Speech distortion
Deep spectrum fusion