中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [84]
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OAI收割 [84]
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期刊论文 [83]
会议论文 [1]
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2024 [2]
2023 [7]
2022 [7]
2021 [8]
2020 [5]
2019 [2]
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Biochemist... [2]
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专题:上海药物研究所
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Ent-labdane-type diterpene glycosides obtained from
Rubus
chingii
Hu and their inhibitory effects on PDE5A activity
期刊论文
OAI收割
FITOTERAPIA, 2024, 卷号: 173, 页码: 14
作者:
Yu, Jun-dong
;
Wang, Jing-Yi
;
Liu, Jia-yuan
;
Xu, Ye-chun
;
Zhang, Xue
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
diterpene glycosides
Rubus Chingii Hu
PDE5A inhibitory activity
ent-labdane
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16
作者:
Cheng, Chen
;
Ren, Chao
;
Li, Mu-zi
;
Liu, Yi-hui
;
Yao, Ren-qi
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/27
Traditional Chinese medicine
XueBiJing
sepsis
mortality
pharmacokinetic compatibility
polypharmacology
Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 3
作者:
Yu, Lei
;
Zhao, Pengcheng
;
Sun, Yaoliang
;
Zheng, Zening
;
Du, Wenhao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/01/26
Repurposed Fenoprofen Targeting SaeR Attenuates Staphylococcus aureus Virulence in Implant-Associated Infections
期刊论文
OAI收割
ACS CENTRAL SCIENCE, 2023, 页码: 20
作者:
Jiang, Feng
;
Chen, Yingjia
;
Yu, Jinlong
;
Zhang, Feiyang
;
Liu, Qian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
ETCM v2.0: An update with comprehensive resource and rich annotations for traditional Chinese medicine
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2559-2571
作者:
Zhang, Yanqiong
;
Li, Xin
;
Shi, Yulong
;
Chen, Tong
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
Traditional Chinese medicine
Database
Target identification
Network visualization
New drug research and development
Molecular mechanism
Quality marker
Drug repurposing
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region
期刊论文
OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 2, 页码: 107942
作者:
Jiang, Hao
;
Zu, Shijia
;
Lu, Yu
;
Sun, Zhongya
;
Adeerjiang, Akejiang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
Small GTPases
Crystal structures of RhoA
Dynamics of switch II
Molecular dynamics simulations
Allosteric pocket
Paraventricular nucleus-central amygdala oxytocinergic projection modulates pain-related anxiety-like behaviors in mice
期刊论文
OAI收割
CNS NEUROSCIENCE & THERAPEUTICS, 2023, 页码: 14
作者:
Li, Yu-Jie
;
Du, Wei-Jia
;
Liu, Rui
;
Zan, Gui-Ying
;
Ye, Bing-Lu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
anxiety
central nucleus of the amygdala
oxytocin
pain
paraventricular nucleus
Further undescribed cembranoids from South China Sea soft coral Sarcophyton ehrenbergi: Structural elucidation and biological evaluation
期刊论文
OAI收割
PHYTOCHEMISTRY, 2023, 卷号: 206, 页码: 9
作者:
Wu, Meng-Jun
;
Yu, Dan-Dan
;
Du, Ye-Qing
;
Zhang, Juan
;
Su, Ming-Zhi
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
Sarcophyton ehrenbergi
Sarcophytidae
Soft coral
Diterpenoids
Cembranoid
?-Glucosidase inhibitor
Phenotypic screening-based drug discovery of furan-2-carboxylic acid derivatives for the amelioration of type 2 diabetes mellitus (T2DM)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 246, 页码: 11
作者:
Chen, Lili
;
Huang, Suling
;
Ye, Yangliang
;
Shen, Yu
;
Xu, Tifei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
Phenotypic screening
Gluconeogenesis
Furan-2-carboxylic acid
T2DM
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 19
作者:
Hu, Cheng-Long
;
Chen, Bing-Yi
;
Li, Zijuan
;
Yang, Tianbiao
;
Xu, Chun-Hui
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/13