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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
采集方式
OAI收割 [11]
内容类型
期刊论文 [11]
发表日期
2023 [1]
2021 [1]
2019 [1]
2018 [3]
2017 [1]
2016 [2]
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专题:上海药物研究所
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A procedure for producing an anti-AXL nanobody in E. coli
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106268
作者:
Lan, Zhongyun
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/27
AXL
Nanobody
Expression
Purification
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:
Du, Daohai
;
Xu, Dandan
;
Zhu, Licheng
;
Stazi, Giulia
;
Zwergel, Clemens
  |  
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2021/08/17
Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 317-333
作者:
Shao, Jingwei
;
Zhu, Kongkai
;
Du, Daohai
;
Zhang, Yuanyuan
;
Tao, Hongrui
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
PRMT5 inhibitors
N-Substituted 1,2,3,4-tetrahydroisoquinoline derivatives
Anti-tumor
Qualitative and quantitative analysis of Porana sinensis Hemsl by UHPLC-Q-Exactive MS, TLC autographic method and DART-MS
期刊论文
OAI收割
Phytochemical analysis : PCA, 2018
作者:
Chen, Zhiyong
;
Wang, Mengmeng
;
Yang, Yuanyuan
;
Du, Xia
;
Zhang, Zijia
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Comparative study of chemical composition and active components against α-glucosidase of various medicinal parts of Morus alba L
期刊论文
OAI收割
Biomedical chromatography : BMC, 2018, 卷号: 32, 期号: 11, 页码: e4328
作者:
Chen, Zhiyong
;
Du, Xia
;
Yang, Yuanyuan
;
Cui, Xiaomin
;
Zhang, Zijia
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Bavachinin analogues as agonists of pan-peroxisome proliferator-activated receptors
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2018, 卷号: 27, 期号: 7, 页码: 1851-1862
作者:
Yi, Jingyu
;
Du, Guoxin
;
Zhao, Yuanyuan
;
Zhang, Liuqiang
;
Li, Bo
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Bavachinin
Metabolic syndrome
PPARs
Reporter gene assaysThese authors contributed equally: Jingyu Yi, Guoxin Du
Design, Synthesis, and Structure-Activity Relationships of Bavachinin Analogues as Peroxisome Proliferator-Activated Receptor Agonists
期刊论文
OAI收割
CHEMMEDCHEM, 2017, 卷号: 12, 期号: 2, 页码: 183-193
作者:
Du, Guoxin
;
Zhao, Yuanyuan
;
Feng, Li
;
Yang, Zhuo
;
Shi, Jiye
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
bavachinin
diabetes mellitus
PPAR
reporter gene assays
structure-activity relationships
Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 15, 页码: 3813-3817
作者:
Wu, Yunlong
;
Hu, Junchi
;
Ding, Hong
;
Chen, Limin
;
Zhang, Yuanyuan
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
EZH2
Epigenetics
PRC2
Computational drug design
Pharmacophore-based virtual screening
Identification of novel small-molecule inhibitors targeting menin-MLL interaction, repurposing the antidiarrheal loperamide
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2016, 卷号: 14, 期号: 36, 页码: 8503-8519
作者:
Yue, Liyan
;
Du, Juanjuan
;
Ye, Fei
;
Chen, Zhifeng
;
Li, Lianchun
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Mapping the Functional Binding Sites of Cholesterol in beta(2)-Adrenergic Receptor by Long-Time Molecular Dynamics Simulations
期刊论文
OAI收割
JOURNAL OF PHYSICAL CHEMISTRY B, 2013, 卷号: 117, 期号: 4, 页码: 1085-1094
作者:
Cang, Xiaohui
;
Du, Yun
;
Mao, Yanyan
;
Wang, Yuanyuan
;
Yang, Huaiyu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08