中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [91]
采集方式
OAI收割 [91]
内容类型
期刊论文 [90]
会议论文 [1]
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2024 [2]
2023 [6]
2022 [8]
2021 [7]
2020 [10]
2019 [5]
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浏览/检索结果:
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专题:上海药物研究所
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Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16
作者:
Han, Fanghui
;
Zhao, Tingting
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/02/19
SSTR5 antagonist
Gallbladder emptying
Cholesterol gallstones
Limonoids and alkaloids from
Tetradium
austrosinense
(Hand.-Mazz.) TG Hartley
期刊论文
OAI收割
FITOTERAPIA, 2024, 卷号: 172, 页码: 5
作者:
Han, Feng
;
Yao, Jia-Ying
;
Tan, Jun-Jie
;
Qin, Nan
;
Jiang, Yu-Xia
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/19
Rutaceae
Tetradium austrosinense
Limonoids
Alkaloids
TDDFT-ECD calculation
Anti-inflammation
Original Research Response to programmed cell death protein 1 antibody in patients with Epstein-Barr virus-associated intrahepatic cholangiocarcinoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF CANCER, 2023, 卷号: 194, 页码: 9
作者:
He, Wen-Zhuo
;
Huang, Yu-Hua
;
Hu, Wan-Ming
;
Wang, Fang
;
Xu, Yu-Xia
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/11
Epstein-Barr virus
Intrahepatic cholangiocarcinoma
Programmed cell death protein 1
Immunotherapy
B-seco Limonoids with anti-inflammatory activity from Tetradium fraxinifolium (Hook.) TGHartley
期刊论文
OAI收割
FITOTERAPIA, 2023, 卷号: 169, 页码: 6
作者:
Jiang, Yu-Xia
;
Yao, Jia-Ying
;
Qin, Nan
;
Tan, Jun-Jie
;
Han, Feng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Tetradium fraxinifolium
Rutaceae
seco limonoids
Anti-inflammation
RAW264
7 cells
TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1649-1664
作者:
Yang, Wen-ji
;
Han, Fang-hui
;
Gu, Yi-pei
;
Qu, Hui
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
TGR5 agonist
ulcerative colitis
intestinal epithelial cell
apoptosis
cAMP
PKA signaling pathway
c-FLIP
Identification of XAF1 as an endogenous AKT inhibitor
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 7, 页码: 25
作者:
Chen, Min
;
Wang, Kangjunjie
;
Han, Ying
;
Yan, Shukun
;
Yuan, Huairui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
The heparan sulfate mimetic Muparfostat aggravates steatohepatitis in obese mice due to its binding affinity to lipoprotein lipase
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2023, 卷号: 180, 期号: 14, 页码: 1803-1818
作者:
Zhang, Jia
;
Li, Kai
;
Sun, Hao-Ran
;
Sun, Shao-Kun
;
Zhu, Ya-Ting
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
heparan sulfate mimetic
heparanase inhibitor
hepatic steatosis
lipoprotein lipase
obesity
Shape and Shear Stress Impact on the Toxicity of Mesoporous Silica Nanoparticles: In Vitro and In Vivo Evidence
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2023, 卷号: 20, 期号: 6, 页码: 3187-3201
作者:
Cheng, Yaxin
;
Tao, Jinsong
;
Zhang, Yaqi
;
Xi, Long
;
Han, Run
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
mesoporous silica nanoparticles (MSNs)
toxicity
shape
shear stress
in vitro blood flow model
ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 20
作者:
Li, Ni
;
Liu, Qiuli
;
Han, Ying
;
Pei, Siyu
;
Cheng, Bisheng
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
Design and exploration of gut-restricted bifunctional molecule with TGR5 agonistic and DPP4 inhibitory effects for treating ulcerative colitis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 242, 页码: 114697
作者:
Han, Fanghui
;
Ning, Mengmeng
;
Wang, Kai
;
Gu, Yipei
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/21
Bifunctional molecule
Gut-restricted
Ulcerative colitis
TGR5
DPP4