中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [176]
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OAI收割 [176]
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期刊论文 [175]
专著章节 [1]
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2024 [1]
2023 [17]
2022 [14]
2021 [15]
2020 [16]
2019 [14]
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专题:上海药物研究所
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Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14
作者:
Tao, Yimin
;
Lu, Wei
;
Gao, Jinli
;
Yang, Shuangshuang
;
Ruan, Chaoyi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/13
antibody-drug conjugate (ADC)
bioanalysis
anti-drug antibody (ADA)
ligand binding assay (LBA)
ADA-tolerant assay
An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 21
作者:
Wang, Jingyi
;
Lin, Jianbang
;
Chen, Yefei
;
Liu, Jing
;
Zheng, Qiongping
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/01/16
Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model
期刊论文
OAI收割
CELL, 2023, 卷号: 186, 期号: 24, 页码: 5394-+
作者:
Chen, Yefei
;
Hong, Zexuan
;
Wang, Jingyi
;
Liu, Kunlin
;
Liu, Jing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF)
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12
作者:
Wu, Xinyu
;
Wang, Mingchen
;
Cao, Yu
;
Xu, Ying
;
Yang, Ziqun
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/02/27
O-GlcNAcylation
O-GlcNAc transferase
High-throughput screening
Inhibitor
GPR84 regulates pulmonary inflammation by modulating neutrophil functions
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1665-1675
作者:
Wang, Si-wei
;
Zhang, Qing
;
Lu, Dan
;
Fang, You-chen
;
Yan, Xiao-ci
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
GPR84
acute lung injury
inflammation
neutrophil
ROS
antagonist
Proteomics of adjacent-to-tumor samples uncovers clinically relevant biological events in hepatocellular carcinoma
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 8, 页码: 17
作者:
Zhu, Hongwen
;
Lin, Youpei
;
Lu, Dayun
;
Wang, Shisheng
;
Liu, Yuejia
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
proteomics
hepatocellular carcinoma
normal tissue adjacent to tumor
heterogeneity
Photochemically controlled activation of STING by CAIX-targeting photocaged agonists to suppress tumor cell growth
期刊论文
OAI收割
CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 22, 页码: 5956-5964
作者:
Ding, Chunyong
;
Du, Mengyan
;
Xiong, Zhi
;
Wang, Xue
;
Li, Hongji
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
ETCM v2.0: An update with comprehensive resource and rich annotations for traditional Chinese medicine
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2559-2571
作者:
Zhang, Yanqiong
;
Li, Xin
;
Shi, Yulong
;
Chen, Tong
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
Traditional Chinese medicine
Database
Target identification
Network visualization
New drug research and development
Molecular mechanism
Quality marker
Drug repurposing
Paraventricular nucleus-central amygdala oxytocinergic projection modulates pain-related anxiety-like behaviors in mice
期刊论文
OAI收割
CNS NEUROSCIENCE & THERAPEUTICS, 2023, 页码: 14
作者:
Li, Yu-Jie
;
Du, Wei-Jia
;
Liu, Rui
;
Zan, Gui-Ying
;
Ye, Bing-Lu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
anxiety
central nucleus of the amygdala
oxytocin
pain
paraventricular nucleus