机构

• 上海药物研究所 [43]

采集方式

• OAI收割 [43]

内容类型

• 期刊论文 [40]
• 会议论文 [3]

发表日期

• 2024 [1]
• 2023 [2]
• 2022 [4]
• 2021 [4]
• 2020 [1]
• 2019 [3]
• 更多

学科主题

筛选

浏览/检索结果: 共43条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334 作者:  Qin, Ying;  Li, Dekang;  Qi, Chunting;  Xiang, Huaijiang;  Meng, Huyan   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/06 RIPK1  Necroptosis  Type-II kinase inhibitors  Rational design  Lead optimization  Structure-activity relationship  Anti-inflammation  Preclinical drug discovery   Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead 期刊论文  OAI收割 GENES & DISEASES, 2023, 卷号: 10, 期号: 2, 页码: 403-414 作者:  Li, Hui-yu;  Qi, Wei-liang;  Wang, Yu-xiang;  Meng, Ling-hua   |  收藏  |  浏览/下载：117/0  |  提交时间：2023/10/17 Biomarkers  Covalent KRasG12Cinhibitors  Drug resistance  Human cancers  KRASG12Cmutation   Intranasal delivery of replicating mRNA encoding hACE2-targeting antibody against SARS-CoV-2 Omicron infection in the hamster 期刊论文  OAI收割 ANTIVIRAL RESEARCH, 2023, 卷号: 209, 页码: 9 作者:  Zhang, Ya-Nan;  Zhang, Hong-Qing;  Wang, Gui-Feng;  Zhang, Zhe-Rui;  Li, Jia-Qi   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/04/10 Omicron  VEEV VRP  Replicable mRNA   Targeting PI3K alpha overcomes resistance to KRas(G12C) inhibitors mediated by activation of EGFR and/or IGF1R 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12 作者:  Qi, Wei-liang;  Li, Hui-yu;  Wang, Yi;  Xu, Lan;  Deng, Jie-ting   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/04/10 AMG510  KRas(G12C)  PI3K  drug resistance  combination therapy   First clinical applications for the NIR-II imaging with ICG in microsurgery 期刊论文  OAI收割 FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 卷号: 10, 页码: 1042546 作者:  Wu, Yifan;  Suo, Yongkuan;  Wang, Zheng;  Yu, Yifeng;  Duan, Shuang   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/03/21 indocyanine green (ICG)  near-infrared II (NIR-II) imaging  fluorescenceguided surgery  vascular anastomosis  flap reconstruction   Structural basis for the tethered peptide activation of adhesion GPCRs 期刊论文  OAI收割 NATURE, 2022, 页码: 41 作者:  Ping, Yu-Qi;  Xiao, Peng;  Yang, Fan;  Zhao, Ru-Jia;  Guo, Sheng-Chao   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/06/15 Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma 期刊论文  OAI收割 CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218 作者:  Chen, Zi-qi;  Cao, Zhe-rui;  Wang, Yi;  Zhang, Xi;  Xu, Lan   |  收藏  |  浏览/下载：54/0  |  提交时间：2021/12/16 CYH33  MYC  P300  BET  B cell lymphoma  PI3K   Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文  OAI收割 JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251 作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen   |  收藏  |  浏览/下载：112/0  |  提交时间：2021/11/04 PDE4  Arctigenin  Psoriasis  Inflammation   Competitive CatSper Activators of Progesterone from Rhynchosia volubilis 期刊论文  OAI收割 PLANTA MEDICA, 2021, 页码: 10 作者:  Xiang, Jin;  Kang, Hang;  Li, Hong-Gang;  Shi, Yu-Long;  Zhang, Ya-Li   |  收藏  |  浏览/下载：47/0  |  提交时间：2021/11/04 Leguminosae  Rhynchosia volubilis  CatSper  prenylated isoflavonoids  rhynchones A - E   Aristolochic acid I induces impairment in spermatogonial stem cell in rodents 期刊论文  OAI收割 TOXICOLOGY RESEARCH, 2021, 卷号: 10, 期号: 3, 页码: 436-445 作者:  Liu, Yongzhen;  He, Xiang;  Wang, Yuli;  Zhou, Houzu;  Zhang, Yuan   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/21 aristolochic acid I  spermatogenesis  spermatogonial stem cells  apoptosis  P53  BAX