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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [15]
采集方式
OAI收割 [15]
内容类型
期刊论文 [15]
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2022 [2]
2021 [1]
2020 [1]
2019 [1]
2017 [3]
2016 [2]
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专题:上海药物研究所
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Multi-omics analysis reveals the pathogenesis of db/db mice diabetic kidney disease and the treatment mechanisms of multi-bioactive compounds combination from Salvia miltiorrhiza
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 16
作者:
Xu, Zhuo
;
Xiang, Xiang
;
Su, Shulan
;
Zhu, Yue
;
Yan, Hui
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/12/13
multi-bioactive compounds combination
diabetic kidney disease
multi-omics
Salvia miltiorrhiza
PI3K/Akt/FoxO signaling pathways
A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease
期刊论文
OAI收割
Journal of Nanobiotechnology, 2022, 卷号: 20, 期号: 1
作者:
Zeng,Feng
;
Shi,Yahong
;
Wu,Chunni
;
Liang,Jianming
;
Zhong,Qixin
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/15
Ceria nanoparticles
Reactive oxygen species
Inflammatory bowel disease
Macrophages
Proinflammatory microenvironment
Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence
期刊论文
OAI收割
NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089
作者:
Bai, Xiangd
;
Wang, Hanchen
;
Ma, Liya
;
Xu, Yongchao
;
Gan, Jiefeng
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2022/01/18
Phase I dose-escalation and expansion study of PARP inhibitor, fluzoparib (SHR3162), in patients with advanced solid tumors
期刊论文
OAI收割
CHINESE JOURNAL OF CANCER RESEARCH, 2020, 卷号: 32, 期号: 3, 页码: 370-+
作者:
Li, Huiping
;
Liu, Rongrui
;
Shao, Bin
;
Ran, Ran
;
Song, Guohong
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/12/24
Phase I
PARP inhibitor (fluzoparib)
solid tumor
pharmacokinetics
safety
antitumor activity
Design, Synthesis and Pharmacological Evaluation of Novel Hsp90N-terminal Inhibitors Without Induction of Heat Shock Response
期刊论文
OAI收割
CHEMISTRYOPEN, 2019, 卷号: 8, 期号: 3, 页码: 344-353
作者:
Liu, Peng
;
Chen, Xiangling
;
Zhu, Jianming
;
Li, Bo
;
Chen, Zhaoqiang
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
autophagy
Hsp72
Hsp90 inhibitor
triazines
antitumor activity
Co-Delivery of Trichosanthin and Albendazole by Nano-Self Assembly for Overcoming Tumor Multidrug-Resistance and Metastasis
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2017, 卷号: 9, 期号: 32, 页码: 26648-26664
作者:
Tang, Yisi
;
Liang, Jianming
;
Wu, Aihua
;
Chen, Yingzhi
;
Zhao, Pengfei
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Multidrug resistance
trichosanthin
albendazole
albumin nanoparticles
silver nanoparticles
metastasis
Regioselectivity and Mechanism of Synthesizing N-Substituted 2-Pyridones and 2-Substituted Pyridines via Metal-Free C-O and C-N Bond-Cleaving of Oxazoline[3,2-a]pyridiniums
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Li, Bo
;
Xue, Susu
;
Yang, Yang
;
Feng, Jia
;
Liu, Peng
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf~(V600E) inhibitors
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 7, 页码: 1057-1068
作者:
Wang Guimin
;
Wang Xiang
;
Zhu Jianming
;
Guo Binbin
;
Yang Zhuo
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
B-Raf~(V600E) inhibitor
anticancer
vemurafenib
deazapurine
fragment reassembly
molecular docking
structure-activity relationship
Synthesis and decreasing A beta content evaluation of arctigenin-4-yl carbamate derivatives
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 13, 页码: 2988-2991
作者:
Xu, Xingyu
;
Li, Cong
;
Lei, Min
;
Zhu, Zhiyuan
;
Yan, Jianming
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/01/08
Arctigenin (ATG)
Natural product
Arctigenin-4-yl 3-carbamate
Structure-activity relationships (SARs)
Alzheimer's disease (AD)
Facile Synthesis of Substituted 4-Alkoxy-2-oxazolines and Exploration of the Reaction Mechanism
期刊论文
OAI收割
SYNTHESIS-STUTTGART, 2016, 卷号: 48, 期号: 9, 页码: 1331-1343
作者:
Zhu, Jianming
;
Li, Xiaolong
;
Wang, Guimin
;
Li, Bo
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
4-alkoxy-2-oxazoline
benzonitrile
beta-hydroxyacetal
trifluoromethanesulfonic acid
reaction mechanism
quantum chemistry calculation