机构

• 上海药物研究所 [86]

采集方式

• OAI收割 [86]

内容类型

• 期刊论文 [85]
• 会议论文 [1]

发表日期

• 2023 [7]
• 2022 [10]
• 2021 [6]
• 2020 [9]
• 2019 [4]
• 2018 [8]
• 更多

学科主题

• Chemistry [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共86条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of Dual Function Agents That Exhibit Anticancer Activity via Catastrophic Nicotinamide Adenine Dinucleotide Depletion 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16694-16703 作者:  Fu, Yixian;  Huang, Yahui;  Zhou, Chenchen;  Li, Xinge;  Dong, Guoqiang   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/01/26 Development of PI3Kγ selective inhibitors: the strategies and application 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 10 作者:  Gu, Dong-Yan;  Zhang, Meng-Meng;  Li, Jia;  Zhou, Yu-Bo;  Sheng, Rong   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/08 PI3K  PI3K gamma inhibitors  isoform selectivity  drug development  rational drug design   Restoring Wnt signaling in a hormone-simulated postpartum depression model remediated imbalanced neurotransmission and depressive-like behaviors 期刊论文  OAI收割 MOLECULAR MEDICINE, 2023, 卷号: 29, 期号: 1, 页码: 18 作者:  Ye, Binglu;  Yuan, Yawei;  Liu, Rui;  Zhou, Haitao;  Li, Yujie   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17 Postpartum depression (PPD)  Neurotransmission  Hippocampus  CA1  Wnt signaling   Pharmacological characterization of the small molecule 03A10 as an inhibitor of α-synuclein aggregation for Parkinson's disease treatment 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 6, 页码: 1122-1134 作者:  Wang, Qing;  Yao, Sheng;  Yang, Ze-xian;  Zhou, Chen;  Zhang, Yu   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/27 Parkinson's disease  alpha-synuclein aggregation  protein-protein interaction  03A10  MPTP/p model  enema inoculation model   Stimuli-activatable PROTACs for precise protein degradation and cancer therapy 期刊论文  OAI收割 SCIENCE BULLETIN, 2023, 卷号: 68, 期号: 10, 页码: 1069-1085 作者:  Gao, Jing;  Yang, Lei;  Lei, Shumin;  Zhou, Feng;  Nie, Huijun   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 PROTAC  Stimuli-activatable prodrug  Precise protein degradation  Nanomedicine  Combinatory therapy   Discovery of 4-oxo-4,5-dihydropyrazolo[1,5-a]quinoxaline-7-carboxamide derivatives as PI3K alpha inhibitors via virtual screening and docking-based structure optimization 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 86, 页码: 15 作者:  Gu, Dongyan;  Zhang, Mengmeng;  Cai, Lvtao;  Wang, Chang;  Zhou, Yu -Bo   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/10/17 PI3K alpha inhibitors  Virtual screening  Structure optimization   Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 18, 页码: 11 作者:  Xu, Haiyu;  Li, Shufen;  Liu, Jiayuan;  Cheng, Jinlong;  Kang, Liping   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/10/17 COVID-19  traditional Chinese medicine  TCMT-NDRD  antivirus  anti-inflammation   Chantriolides F-P, Highly Oxidized Withanolides with Hepatoprotective Activity from Tacca chantrieri 期刊论文  OAI收割 MOLECULES, 2022, 卷号: 27, 期号: 23, 页码: 18 作者:  Yang, Yue;  Zhou, Fei;  Wang, Min;  Turanazarov, Mukhammadrizo;  Wang, Xiao-Rong   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/04/10 Tacca chantrieri  structural elucidation  withanolides  chantriolides F-P  hepatoprotective effect   Redox Dyshomeostasis with Dual Stimuli-Activatable Dihydroartemisinin Nanoparticles to Potentiate Ferroptotic Therapy of Pancreatic Cancer 期刊论文  OAI收割 SMALL METHODS, 2022, 页码: 13 作者:  Wang, Yingjie;  Chen, Fangmin;  Zhou, Huiling;  Huang, Lujia;  Ye, Jiayi   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/04/10 combinatory therapy  dual stimuli-responsive  ferroptosis  immunotherapy  pancreatic cancer   Enantiomeric pairs of meroterpenoids with 11/5/6 spiro-heterocyclic systems from Hypericum kouytchense 期刊论文  OAI收割 ORGANIC CHEMISTRY FRONTIERS, 2022, 页码: 9 作者:  Huang, Jin-Chang;  Sheng, Li;  Zong, Jian-Fa;  Zhou, Yu-Bo;  Li, Jia   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/12/13