中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [33]
合肥物质科学研究院 [24]
近代物理研究所 [10]
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期刊论文 [168]
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Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis The EXIT-SEP Randomized Clinical Trial
期刊论文
OAI收割
JAMA INTERNAL MEDICINE, 2023, 卷号: 183, 期号: 7, 页码: 647-655
作者:
Liu, Songqiao
;
Yao, Chen
;
Xie, Jianfeng
;
Liu, Hong
;
Wang, Hongliang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 6, 页码: 31
作者:
Zhang, Hui
;
Li, Jiaming
;
Yu, Yang
;
Ren, Jie
;
Liu, Qiang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/11/17
Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23
作者:
Chen, Lili
;
Yun, Ying
;
Guo, Shimeng
;
Wang, Xiaoyan
;
Xiong, Muya
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 2, 页码: 739-753
作者:
Xie, Zhifu
;
Zhang, Mei
;
Song, Qian
;
Cheng, Long
;
Zhang, Xinwen
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Hypercholesterolemia
Atherosclerosis
Liver
ATP-Citrate lyase (ACLY)
Lipogenesis
Cholesterol efflux
ACLY inhibitor
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors
期刊论文
OAI收割
PROTEIN & CELL, 2023, 卷号: 14, 期号: 1, 页码: 17-27
作者:
Zang, Yi
;
Su, Mingbo
;
Wang, Qingxing
;
Cheng, Xi
;
Zhang, Wenru
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
high-throughput screening
SARS
CoV-2
main
papain-like
proteases
Design of the PMT underwater cascade implosion protection system for JUNO
期刊论文
OAI收割
Journal of Instrumentation, 2023, 卷号: 18, 期号: 2, 页码: P02013
作者:
He, Miao
;
Qin, Zhonghua
;
Hou, Shaojing
;
Jing, Xiaoping
;
Liu, Hongbang
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/03/29
Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425
作者:
Sun, Yin
;
Tang, Haotian
;
Wang, Xiaoyan
;
Feng, Fang
;
Fan, Tiantian
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/08/16
TBK1 inhibitors
1H-pyrazolo[3
4-b]pyridine
structure-activity relationships (SARs)
immune response
cancer therapy
Systematic Analysis of Lysine Acetylation Reveals Diverse Functions in Azorhizobium caulinodans Strain ORS571
期刊论文
OAI收割
MICROBIOLOGY SPECTRUM, 2022, 页码: 18
作者:
Liu, Yanan
;
Liu, Xiaolin
;
Dong, Xiaoyan
;
Yin, Zhiqiu
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/01/11
lysine acetylation
acetylome
Azorhizobium caulinodans ORS571
deacetylase
chemotaxis
Changes in Disposition of Ezetimibe and Its Active Metabolites Induced by Impaired Hepatic Function: The Influence of Enzyme and Transporter Activities
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 12, 页码: 22
作者:
Xie, Ningjie
;
Wang, Hong
;
Qin, Hua
;
Guo, Zitao
;
Xue, Hao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
hepatic impairment
ezetimibe
active metabolites
phase II enzymes
transporters
first-pass metabolism
inhibitory bile acids
The Aurora Kinase Inhibitor CYC116 Promotes the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells
期刊论文
OAI收割
MOLECULES AND CELLS, 2022, 卷号: 45, 期号: 12, 页码: 923-934
作者:
Ji, Sijia
;
Tu, Wanzhi
;
Huang, Chenwen
;
Chen, Ziyang
;
Ren, Xinyue
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
Aurora kinase inhibitor
cardiomyocyte differen-tiation
cell cycle
human pluripotent stem cell
maturation