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筛选

浏览/检索结果: 共556条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Inulin-like polysaccharide ABWW may impede CCl4 induced hepatic stellate cell activation through mediating the FAK/PI3K/AKT signaling pathway in vitro & in vivo 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2024, 卷号: 326, 页码: 15 作者:  Dai, Xiaolan;  Du, Zhenyun;  Jin, Can   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/02/19 Fructan  Hepatic fibrosis  Hepatic stellate cells  FAK/PI3K/AKT   A novel strategy for treating oncogene-mutated tumors by targeting tumor microenvironment and synergistically enhancing anti-PD-1 immunotherapy 期刊论文  OAI收割 CANCER COMMUNICATIONS, 2024, 页码: 5 作者:  Liu, Yingqiang;  Tong, Linjiang;  Zhang, Mengge;  Zhang, Qi;  Liu, Qiupei   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/13 From bench to bedside: current development and emerging trend of KRAS-targeted therapy 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18 作者:  Chen, Yi;  Liu, Qiu-pei;  Xie, Hua;  Ding, Jian   |  收藏  |  浏览/下载：28/0  |  提交时间：2024/01/16 KRAS mutation  KRAS(G12C) inhibitor  Pan-KRAS inhibitor  SHP2 allosteric inhibitor  SOS1 inhibitor  combination therapy   Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764 作者:  Liu, Yingqiang;  Zhan, Zhengsheng;  Kang, Zhuang;  Li, Mengyuan;  Lv, Yongcong   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/26 Small molecule inhibitor  Tumor microenvironment  Immune-checkpoint  immune-deficient mouse models  including temozolomide (TMZ) insensitive tumors. Notably   Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：58/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   Hepatic glucuronyl C5-epimerase combats obesity by stabilising GDF15 期刊论文  OAI收割 JOURNAL OF HEPATOLOGY, 2023, 卷号: 79, 期号: 3, 页码: 14 作者:  He, Fei;  Jiang, Haowen;  Peng, Chang;  Wang, Tingting;  Xiao, Rongrong   |  收藏  |  浏览/下载：61/0  |  提交时间：2023/10/17 Glucuronyl C5-epimerase  Growth differentiation factor-15  Obesity  Energy expenditure  Ubiquitination   A longitudinal resource for population neuroscience of school-age children and adolescents in China 期刊论文  OAI收割 SCIENTIFIC DATA, 2023, 卷号: 10, 期号: 1, 页码: 24 作者:  Fan, Xue-Ru;  Wang, Yin-Shan;  Chang, Da;  Yang, Ning;  Rong, Meng-Jie   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/12/11 Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16 作者:  Chen, Yun;  Ning, Yi;  Chen, Zhiwei;  Xue, Yaping;  Wu, Qingyun   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Apoptosis  Diffuse large B-Cell lymphoma  Interleukin-1 receptor associated kinase 4  Structure-based drug design  2  3-Dihydrobenzofuran   Development of HSP90 inhibitors-SN38 conjugates for cancer treatment 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 11 作者:  Cao, Yuting;  Shen, Qianqian;  Ding, Mengyuan;  Chen, Yi;  Lu, Wei   |  收藏  |  浏览/下载：64/0  |  提交时间：2023/10/17 HSP90  SN38 conjugate  Drug accumulation  Cancer treatment   Dysregulation of iron homeostasis by TfR-1 renders EZH2 wild type diffuse large B-cell lymphoma resistance to EZH2 inhibition 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12 作者:  Yu, Lei;  Wang, Ya-fang;  Xiao, Jian;  Shen, Qian-qian;  Chi, Shuai-shuai   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 diffuse large B-cell lymphoma  EZH2  TfR-1  GPX4  ferroptosis  HH2853