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浏览/检索结果: 共255条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Metabolic regulation of homologous recombination repair by MRE11 lactylation 期刊论文  OAI收割 CELL, 2024, 卷号: 187, 期号: 2, 页码: 40 作者:  Chen, Yuping;  Wu, Jinhuan;  Zhai, Linhui;  Zhang, Tingting;  Yin, Hui   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/04/09 The emergence of machine learning force fields in drug design 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2024, 页码: 36 作者:  Chen, Mingan;  Jiang, Xinyu;  Zhang, Lehan;  Chen, Xiaoxu;  Wen, Yiming   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/02/19 computational chemistry  drug design  force field  machine learning  molecular modeling   Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764 作者:  Liu, Yingqiang;  Zhan, Zhengsheng;  Kang, Zhuang;  Li, Mengyuan;  Lv, Yongcong   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/26 Small molecule inhibitor  Tumor microenvironment  Immune-checkpoint  immune-deficient mouse models  including temozolomide (TMZ) insensitive tumors. Notably   Bioinspired soft robots for deep-sea exploration 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 10 作者:  Li, Guorui;  Wong, Tuck-Whye;  Shih, Benjamin;  Guo, Chunyu;  Wang, Luwen   |  收藏  |  浏览/下载：31/0  |  提交时间：2024/01/03 SOTEM exploration and reservoir structure analysis of Yangbajain geothermal field, Xizang 期刊论文  OAI收割 CHINESE JOURNAL OF GEOPHYSICS-CHINESE EDITION, 2023, 卷号: 66, 期号: 11, 页码: 4805-4816 作者:  Chen WeiYing;  Xue GuoQiang;  Zhao Ping;  Ren WangQi;  He YiMing   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/02 Yangbajain geothermal field  SOTEM  Electrical structure  Migration pathway  Reservoir structure   Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9 作者:  Lu, Shiwei;  Zhang, Feng;  Gong, Jiahao;  Huang, Jian;  Zhu, Guanghao   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 Cytochrome P450 3A4 (CYP3A4)  Inhibitors  Isoquinoline chalcones  Orally active   Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11 作者:  Zhao, Yitian;  Zhang, Min;  Hou, Xudong;  Han, Jiaxin;  Qin, Xiaoya   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Salicylanilide  hPL inhibitor  Structure -activity relationship  Anti -obesity   Three-dimensional electrical structure model of the Yangbajain geothermal field in Tibet: Evidence obtained from magnetotelluric data 期刊论文  OAI收割 SCIENCE CHINA-EARTH SCIENCES, 2023, 页码: 14 作者:  Xue, Guoqiang;  Chen, Weiying;  Zhao, Ping;  Ren, Wangqi;  He, Yiming   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/01/02 Geothermal field  Magnetotelluric  Partial melt body  3D electrical structure  Thermal reservoir geological model   Investigation of urban active faults using the short-offset transient electromagnetic method: an example from Shunping, Hebei Province, China 期刊论文  OAI收割 JOURNAL OF GEOPHYSICS AND ENGINEERING, 2023, 卷号: 20, 期号: 4, 页码: 874-882 作者:  Song, Wanting;  Chen, Weiying;  He, Yiming;  Lei, Kangxin;  Lv, Pengfei   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/01/02 buried active faults  SOTEM  data analysis  resistivity anomaly   Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612 作者:  Wang, Xiaomin;  Xu, Jun;  Sun, Yiming;  Cao, Siyuwei;  Zeng, Hanlin   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 HDAC inhibitors  Drug resistance  Histone methylation  Histone acetylation  Epigenetic interplay  Hedgehog pathway  ZIC1  LIFR  Combination therapy  Breast cancer