中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [25]
合肥物质科学研究院 [17]
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期刊论文 [120]
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Structure-based optimization of indoline-containing compounds as second generation inhibitors of NF-KB-inducing kinase (NIK)
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1295, 页码: 19
作者:
Cheng, Jing
;
Yan, Ziqin
;
Li, Xinzhi
;
Liu, Chen
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Kinase inhibitor
NIK
NF-KB2
Indoline
COT
Cytotoxicity
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:
Cheng, Jing
;
Yan, Ziqin
;
Jiang, Kailong
;
Liu, Chen
;
Xu, Dehua
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/19
Design and Analysis of High Temperature Superconducting Current Leads for CRAFT TF Magnet
期刊论文
OAI收割
IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY, 2023, 卷号: 33
作者:
Han, Quan
;
Lu, Kun
;
Song, Yuntao
;
Ding, Kaizhong
;
Liu, Chen
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2023/11/10
Analysis
Comprehensive Research Facility for Fusion Technology (CRAFT)
high-temperature superconducting current leads (HTSCL)
structure design
toroidal field (TF) magnet
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Electrochemical Determination of Iron(III) in River Water by Differential Pulse Voltammetry (DPV) Using a Poly(3,4-Ethylenedioxythiophene)-Polystyrene Sulfonate co-Polymer/Gold Nanoparticle Modified Gold Microelectrode
期刊论文
OAI收割
ANALYTICAL LETTERS, 2023, 页码: 14
作者:
Tao, Wenyan
;
Ye, Mingguo
;
Liu, Ying
;
Lin, Zhenjia
;
Wang, Chenchen
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
Differential pulse voltammetry (DPV)
electrochemical impedance spectroscopy (EIS)
Fe(III)
gold nanoparticle (AuNP)
poly(3,4-ethylenedioxythiophene)-polystyrenesulfonate(PEDOT-PSS) co-polymer
river water
Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 14, 期号: 8, 页码: 1073-1078
作者:
Seydimemet, Mengnisa
;
Yang, Yixuan
;
Lv, Yuhan
;
Liu, Jiaxiang
;
Yan, Ziqin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
DNA-encoded library technology
Pyrimidine-focusedDNA-encodedlibrary
BRD4
Affinity screening
Inhibitor
China?s enhanced urban wastewater treatment increases greenhouse gas emissions and regional inequality
期刊论文
OAI收割
WATER RESEARCH, 2023, 卷号: 230, 页码: 11
作者:
Huang, Yujun
;
Meng, Fanlin
;
Liu, Shuming
;
Sun, Siao
;
Smith, Kate
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/02/27
Greenhouse gas
Wastewater treatment plants
Historical trajectory
Driving forces
Spatial inequality
Land-Cover Classification With High-Resolution Remote Sensing Images Using Interactive Segmentation
期刊论文
OAI收割
IEEE ACCESS, 2023, 卷号: 11, 页码: 6735-6747
作者:
Xu, Leilei
;
Liu, Yujun
;
Shi, Shanqiu
;
Zhang, Hao
;
Wang, Dan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/03/03
Deep learning
CNN
sample
interactive segmentation
Synthesis and Biological Evaluation of Sclareolide-Indole Conjugates and Their Derivatives
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 4, 页码: 1737
作者:
Cheng, Ying
;
Lyu, Xilin
;
Liu, Chen
;
Wang, Xiancheng
;
Cheng, Jing
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
sclareolide
indole
polyphenol
acetal
antitumor activity
PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 1, 页码: 157-173
作者:
Sun, Mingming
;
Li, Leilei
;
Niu, Yujia
;
Wang, Yingzhi
;
Yan, Qi
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/03/27
Lung cancer
Metabolic reprogramming
Post-translational modification
PRMT6
Pentose phosphate pathway flux
Glycolysis
6-Phospho-gluconate dehydrogenase
a-enolase
ENO1