中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [55]
采集方式
OAI收割 [55]
内容类型
期刊论文 [54]
会议论文 [1]
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2024 [1]
2023 [4]
2022 [8]
2021 [5]
2020 [4]
2019 [3]
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学科主题
Chemistry [1]
Pharmacolo... [1]
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专题:上海药物研究所
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Visualization of nasal powder distribution using biomimetic human nasal cavity model
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 392-404
作者:
Su, Jiawen
;
Liu, Yan
;
Sun, Hongyu
;
Naeem, Abid
;
Xu, Huipeng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Nasal drug deposition
Nasal drug distribution
Nasal drug delivery
Biomimetic nasal model
Nasal powder
Three-dimensional reconstruction
Three-dimensional printing
Structure-Activity Relationship Study of 1H-Pyrrole-3-carbonitrile Derivatives as STING Receptor Agonists
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 9
作者:
Shen, Chang
;
Xu, Peijia
;
Zhang, Changfa
;
Su, Zhaoming
;
Shan, Bin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
cGAS-STING signaling pathway
STING agonists
antitumor immunity
anti-infection immunity
Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2
期刊论文
OAI收割
European journal of medicinal chemistry, 2023, 卷号: 249, 页码: 115129
作者:
Ren, Pengxuan
;
Yu, Changyue
;
Zhang, Ruxue
;
Nie, Tianqing
;
Hu, Qiaoyu
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/26
Spatiotemporal and global profiling of DNA-protein interactions enables discovery of low-affinity transcription factors
期刊论文
OAI收割
NATURE CHEMISTRY, 2023, 页码: 18
作者:
Guo, An-Di
;
Yan, Ke-Nian
;
Hu, Hao
;
Zhai, Linhui
;
Hu, Teng-Fei
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
Flavonoids from the roots and rhizomes of Sophora tonkinensis and their in vitro anti-SARS-CoV-2 activity
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 1, 页码: 65
作者:
Li Zhuo
;
Xie Hang
;
Tang Chunping
;
Feng Lu
;
Ke Changqiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/05/22
Sophora tonkinensis
Flavonoid
Anti-SARS-CoV-2 activity
SARS-CoV-2 3CLpro
SARS-CoV-2 PLpro
Neuroprotective effects of a lead compound from coral via modulation of the orphan nuclear receptor Nurr1
期刊论文
OAI收割
CNS NEUROSCIENCE & THERAPEUTICS, 2022, 页码: 14
作者:
Su, Jian-Wei
;
Yang, Pei
;
Xing, Mei-Mei
;
Chen, Bao
;
Xie, Xia-Hong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
C
elegans
corals-derived compounds
neuroprotection
Nurr1
SH-SY5Y cells
Radical C-H Sulfonation of Arenes: Its Applications on Bioactive and DNA-Encoded Molecules
期刊论文
OAI收割
ORGANIC LETTERS, 2022, 页码: 6
作者:
Zhang, Yue
;
Xia, Shengdi
;
Shi, Wen-xia
;
Lin, Bizhen
;
Su, Xiao-can
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/13
Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Song, Jia
;
Yang, Rui-rui
;
Chang, Jie
;
Liu, Ya-dan
;
Lu, Cheng-hao
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/11/11
cyclic GMP-AMP synthase
covalent inhibitor
inflammatory bowel disease
high-throughput screening
Triazine-Based Covalent DNA-Encoded Libraries for Discovery of Covalent Inhibitors of Target Proteins
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 8
作者:
Li, Linjie
;
Su, Mingbo
;
Lu, Weiwei
;
Song, Hongzhi
;
Liu, Jiaxiang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/09/30
DNA encoded library
covalent library
library design
covalent inhibitors
Deletion of Schizophrenia Susceptibility Gene Ulk4 Leads to Abnormal Cognitive Behaviors via Akt-GSK-3 Signaling Pathway in Mice
期刊论文
OAI收割
SCHIZOPHRENIA BULLETIN, 2022, 页码: 10
作者:
Hu, Ling
;
Zhou, Bing-Yao
;
Yang, Cui-Ping
;
Lu, Da-Yun
;
Tao, Yun-Chao
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/06/15
Unc-51-like kinase 4
schizophrenia
sensorimotor gating
Akt
GSK-3
cerebral cortex