机构

• 上海药物研究所 [10]

采集方式

• OAI收割 [10]

内容类型

• 期刊论文 [10]

发表日期

• 2024 [1]
• 2023 [6]
• 2022 [3]

学科主题

筛选

浏览/检索结果: 共10条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2 期刊论文  OAI收割 STEROIDS, 2024, 卷号: 202, 页码: 8 作者:  Liu, Yaowen;  Nie, Tianqing;  Hou, Jinjun;  Long, Huali;  Zhang, Zijia   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/03/13 3CLpro  SARS-CoV-2  Betulinic acid  Natural product  Inhibitory activity   Preparation and characterization of nanobodies targeting SARS-CoV-2 papain-like protease 期刊论文  OAI收割 PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106267 作者:  Qiao, Huarui;  Li, Lingyun;  Wang, Lu;  Yu, Haijun;  Hu, Fangzheng   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 SARS-CoV-2  Papain like protease (PLpro)  Nanobody  PLpro inhibitor   Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 15 作者:  Wang, Qian;  Chen, Guofeng;  He, Jian;  Li, Jiameng;  Xiong, Muya   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 SARS-CoV-2  papain-like protease  covalent inhibitor  co-crystal structure  in vitro assay   Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches 期刊论文  OAI收割 CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 18, 页码: 4681-4696 作者:  Shao, Qiang;  Xiong, Muya;  Li, Jiameng;  Hu, Hangchen;  Su, Haixia   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2 期刊论文  OAI收割 European journal of medicinal chemistry, 2023, 卷号: 249, 页码: 115129 作者:  Ren, Pengxuan;  Yu, Changyue;  Zhang, Ruxue;  Nie, Tianqing;  Hu, Qiaoyu   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/26 High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors 期刊论文  OAI收割 PROTEIN & CELL, 2023, 卷号: 14, 期号: 1, 页码: 17-27 作者:  Zang, Yi;  Su, Mingbo;  Wang, Qingxing;  Cheng, Xi;  Zhang, Wenru   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27 high-throughput screening  SARS  CoV-2  main  papain-like  proteases   Flavonoids from the roots and rhizomes of Sophora tonkinensis and their in vitro anti-SARS-CoV-2 activity 期刊论文  OAI收割 CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 1, 页码: 65 作者:  Li Zhuo;  Xie Hang;  Tang Chunping;  Feng Lu;  Ke Changqiang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/05/22 Sophora tonkinensis  Flavonoid  Anti-SARS-CoV-2 activity  SARS-CoV-2 3CLpro  SARS-CoV-2 PLpro   Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 10 作者:  Hu, Hangchen;  Wang, Qian;  Su, Haixia;  Shao, Qiang;  Zhao, Wenfeng   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/04/10 Allosteric Modulator  Cysteine 270  Drug Design  Papain-Like Protease  SARS-CoV-2   Parthenolide reveals an allosteric mode to inhibit the deISGylation activity of SARS-CoV-2 papain-like protease 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2022, 卷号: 54, 期号: 8, 页码: 1133-1139 作者:  Zou, Zhihui;  Shan, Huizhuang;  Sun, Demeng;  Xia, Li;  Shi, Yulong   |  收藏  |  浏览/下载：33/0  |  提交时间：2022/11/11 COVID-19  SARS-CoV-2  PLpro  Parthenolide  deISGylation   Discovery of highly potent SARS-CoV-2 M-pro inhibitors based on benzoisothiazolone scaffold 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 58, 页码: 6 作者:  Chen, Weixiong;  Feng, Bo;  Han, Sheng;  Wang, Peipei;  Chen, Wuhong   |  收藏  |  浏览/下载：27/0  |  提交时间：2022/06/15 COVID-19  SARS-CoV-2  Main protease inhibitors  Benzoisothiazolone