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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [214]
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期刊论文 [221]
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Structural Similarity in Natural Products Leading to Sample Misidentification: A Case Study of the Bisbenzylisoquinoline Alkaloids Oxyacanthine and Berbamine
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2025, 卷号: 88, 期号: 1, 页码: 191-198
作者:
Cheng, Yan
;
Akramov, Davlat
;
Yakhshilikova, Lola
;
Zhu, Chengwei
;
Lu, Jie
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:
Guma, Samuel Desta
;
Zhou, Zhaoyin
;
Song, Kang
;
Yang, Feipu
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/12/11
SARS-CoV-2
3CL pro inhibitors
Peptidomimetics
Spiropyrrolidine derivatives
F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13
作者:
Zhang, Qian
;
Yin, Wenhai
;
Chen, Xinyao
;
Zhou, Aimin
;
Zhang, Guixu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/02/28
Direct Reductive
N
-alkylation of Amines with Carboxylic Esters
期刊论文
OAI收割
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 页码: 7
作者:
Zhang, Yuxuan
;
Bonku, Emmanuel Mintah
;
Yang, Xingbang
;
Zhu, Fuqiang
;
Jiang, Xiangrui
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/01/14
Direct reductive
N
-alkylation of amine
One-pot reaction
Grignard reagent
Amidation of ester
Cariprazine
Design, synthesis, and evaluation of novel oxyacanthine derivatives for anti-SARS-CoV-2 activity
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 113, 页码: 5
作者:
Lu, Jie
;
Cheng, Yan
;
Zhang, Yumin
;
Wang, Yi
;
Xia, Bingqing
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/02/28
Bisbenzylisoquinoline alkaloid
Oxyacanthine derivatives
SARS-CoV-2
Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 112, 页码: 5
作者:
Shen, Wen
;
Chen, Xinyao
;
Zhou, Liping
;
Cheng, Yan
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/10/21
COVID-19
SARS-CoV-2 3CL pro inhibitor
Drug design
Antiviral activities
Iron-Catalyzed Cross-Coupling Reactions of Alkyl Grignard Reagents with Alkenyl Carbonate
期刊论文
OAI收割
ADVANCED SYNTHESIS & CATALYSIS, 2024, 页码: 8
作者:
Qin, Hongjian
;
Yang, Xingbang
;
Mintah Bonku, Emmanuel
;
Zhu, Fuqiang
;
Abduahadi, Safomuddin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/12/11
Iron catalysis
Alkylation of alkenyl carbonates
Grignard reagents
Cross-coupling reactions
C(
sp
2)-C(
sp
3) bonds formation
A review of the synthetic strategies toward the antiviral drug tecovirimat
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 页码: 16
作者:
Bonku, Emmanuel Mintah
;
Qin, Hongjian
;
Odilov, Abdullajon
;
Abduahadi, Safomuddin
;
Guma, Samuel Desta
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/11/05
Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 16
作者:
Zheng, Jiefang
;
Zhou, Liping
;
Gong, Xudong
;
Yang, Feipu
;
Cheng, Jiaxin
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/08/22
Triple reuptake inhibitors
5-HT 1A R agonists
Antidepressants
Multimodal serotonergic compounds
Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 111, 页码: 16
作者:
Li, Xiaomei
;
Zhang, Hui
;
Dong, Sanfeng
;
Gao, Xuejie
;
Sun, Haiguo
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/09/26
Multiple myeloma
1-amido-2-one-4-thio-deoxypyranose
TRIP13 inhibitor
In vivo activity