中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [31]
金属研究所 [4]
地理科学与资源研究所 [1]
中国科学院大学 [1]
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OAI收割 [36]
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期刊论文 [36]
会议论文 [1]
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2025 [1]
2024 [2]
2023 [2]
2022 [2]
2021 [3]
2020 [1]
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学科主题
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浏览/检索结果:
共37条,第1-10条
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Design of Selective BRD4 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 18
作者:
Yang, Yueyue
;
Liu, Hongli
;
Yuan, Haoxing
;
Lyu, Kaikai
;
Zhong, Haiyang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Structure-Based Rational Design and Evaluation of BET-Aurora Kinase Dual-Inhibitors for Treatment of Cancers
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Lyu, Kaikai
;
Ren, Ying
;
Mou, Jie
;
Yang, Yunfang
;
Pan, Yaoyao
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/02/28
Design and development of a series of 4-(piperazin-1-yl)pyrimidines as irreversible menin inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 280, 页码: 20
作者:
Luo, Menglan
;
Ye, Yunfei
;
Tang, Lu
;
Kan, Weijuan
;
Chen, Lin
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/11/26
Menin
Covalent inhibitor
Antitumor
Degradation
Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 20
作者:
Shi, Huanyu
;
Tang, Haotian
;
Li, Yan
;
Chen, Danqi
;
Liu, Tongchao
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/04/10
Cancer immunotherapy
SAR study
HPK1 inhibitors
Quinazoline-2
5-diamine
IL-2 production
Design, synthesis and biological evaluation of 4-aminoquinoline derivatives as receptor-interacting protein kinase 2 (RIPK2) inhibitors
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2023, 卷号: 38, 期号: 1, 页码: 282-293
作者:
Fan, Tiantian
;
Ji, Yinchun
;
Chen, Danqi
;
Peng, Xia
;
Ai, Jing
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/04/10
RIPK2 inhibitor
NOD
immunity
inflammation
Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 13
作者:
Luo, Menglan
;
Wu, Qian
;
Yang, Yueyue
;
Sun, Lin
;
Huan, Xiajuan
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/08/30
BET inhibitor
BRD4
Bivalent inhibitor
Anticancer
Discovery of 4-cyclopropyl-3-(2-((1-cyclopropyl-1H-pyrazol-4-yl) amino) quinazolin-6-yl)-N-(3-(trifluoromethyl) phenyl) benzamides as potent discoidin domain receptor inhibitors for the treatment of idiopathic pulmonary fibrosis
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 4, 页码: 1943-1962
作者:
Wang, Qi
;
Tang, Bixi
;
Sun, Dandan
;
Dong, Ying
;
Ji, Yinchun
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/08/16
Idiopathic pulmonary fibrosis
Discoidin domain receptor
Kinase
Inhibitor
Docking
Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16650-16674
作者:
Zhang, Zhuqing
;
Guo, Zuhao
;
Xu, Xiaowei
;
Cao, Danyan
;
Yang, Hong
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收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/06/15
HOW THE SATELLITE CITY IS AFFECTING Co-2 EMISSIONS
期刊论文
OAI收割
CLIMATE CHANGE ECONOMICS, 2021, 页码: 34
作者:
Liao, Danqi
;
Guo, Lisi
;
Liu, Gengyuan
;
Wu, Feng
;
Chen, Caocao
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/11/05
Satellite city
GHG emissions
LEAP
Paris Agreement targets
Discovery of a series of 1H-pyrrolo[2,3-b]pyridine compounds as potent TNIK inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 33, 页码: 127749
作者:
Yang, Bowen
;
Wu, Qian
;
Huan, Xiajuan
;
Wang, Yingqing
;
Sun, Yin
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/03/21
TNIK inhibitor
1H-pyrrolo[2,3-b]pyridine
IL-2 secretion inhibitory