中国科学院机构知识库网格系统: 检索

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	Dehydroberberine Analogue Nanoassemblies for Inducing and Self-Reporting Mitochondrial Dysfunction in Tumor Cells 期刊论文 OAI收割 ACS applied bio materials, 2021, 卷号: 4, 期号: 3, 页码: 2033-2043 作者: Zhang, Rui; An, Ruibing; Gu, Zhanni; Sun, Haifeng; Ye, Deju \| 收藏 \| 浏览/下载：16/0 \| 提交时间：2024/03/15 dehydroberberine fluorescence mitochondria self-assembly self-reporting
	Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20 作者: Zhang, Rui; Li, Heng; Zhang, Xianglei; Li, Jian; Su, Haixia \| 收藏 \| 浏览/下载：44/0 \| 提交时间：2021/05/24 PDE4 inhibitors Tetrahydroisoquinoline Antipsoriasis
	Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent 期刊论文 OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593 作者: Zhang, Xianglei; Dong, Guangyu; Li, Heng; Chen, Wuyan; Li, Jian \| 收藏 \| 浏览/下载：36/0 \| 提交时间：2020/07/01
	Self-assembly of Fluorescent Dehydroberberine Enhances Mitochondria-Dependent Antitumor Efficacy 期刊论文 OAI收割 CHEMISTRY-A EUROPEAN JOURNAL, 2018, 卷号: 24, 期号: 39, 页码: 9812-9819 作者: An, Ruibing; Gu, Zhanni; Sun, Haifeng; Hu, Yuxuan; Yan, Runqi \| 收藏 \| 浏览/下载：29/0 \| 提交时间：2019/01/08 antitumor cell imaging dehydroberberine mitochondria self-assembly
	Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK) 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027 作者: Gu, Zhanni; Wu, Lingyan; Duan, Yanan; Wang, Jiang; Zhou, Shengbin \| 收藏 \| 浏览/下载：40/0 \| 提交时间：2019/01/08 Adenosine 5 '-monophosphate-activated protein kinase AMPK activators Berberine Tetrahydroberberine T2DM
	Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464 作者: Zhou, Shengbin; Duan, Yanan; Wang, Jiang; Zhang, Jin; Sun, Haifeng \| 收藏 \| 浏览/下载：37/0 \| 提交时间：2019/01/08 Tetrahydroberberine 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines Mitochondrial respiration AMPK indirect activators db/db mice
	Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II-III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas 期刊论文 OAI收割 CHEMICAL REVIEWS, 2016, 卷号: 116, 期号: 2, 页码: 422-518 作者: Zhou, Yu; Wang, Jiang; Gu, Zhanni; Wang, Shuni; Zhu, Wei \| 收藏 \| 浏览/下载：38/0 \| 提交时间：2019/01/08
	Fluorescent Coumarin-Artemisinin Conjugates as Mitochondria-Targeting Theranostic Probes for Enhanced Anticancer Activities 期刊论文 OAI收割 CHEMISTRY-A EUROPEAN JOURNAL, 2015, 卷号: 21, 期号: 48, 页码: 17415-17421 作者: Zhang, Xu; Ba, Qian; Gu, Zhanni; Guo, Diliang; Zhou, Yu \| 收藏 \| 浏览/下载：21/0 \| 提交时间：2019/01/08 apoptosis cancer drug delivery imaging agents theranostic probes
	Recent advances in the trifluoromethylation methodology and new CF3-containing drugs 期刊论文 OAI收割 JOURNAL OF FLUORINE CHEMISTRY, 2014, 卷号: 167, 页码: 37-54 作者: Zhu, Wei; Wang, Jiang; Wang, Shuni; Gu, Zhanni; Luis Acena, Jose \| 收藏 \| 浏览/下载：24/0 \| 提交时间：2019/01/08 Trifluoromethylation Methodology Fluorine-containing drugs Pharmaceuticals Biological activity