中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
采集方式
OAI收割 [6]
内容类型
期刊论文 [6]
发表日期
2025 [2]
2024 [3]
2023 [1]
学科主题
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Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:
Guma, Samuel Desta
;
Zhou, Zhaoyin
;
Song, Kang
;
Yang, Feipu
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2024/12/11
SARS-CoV-2
3CL pro inhibitors
Peptidomimetics
Spiropyrrolidine derivatives
A review of the synthetic strategies toward the antiviral drug tecovirimat
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 页码: 16
作者:
Bonku, Emmanuel Mintah
;
Qin, Hongjian
;
Odilov, Abdullajon
;
Abduahadi, Safomuddin
;
Guma, Samuel Desta
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/11/05
Impurity study of tecovirimat
期刊论文
OAI收割
HELIYON, 2024, 卷号: 10, 期号: 9, 页码: 12
作者:
Bonku, Emmanuel Mintah
;
Qin, Hongjian
;
Odilov, Abdullajon
;
Abduahadi, Safomuddin
;
Guma, Samuel Desta
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/08/20
Tecovirimat
Genotoxic impurities
Process development
International Conference on Harmonization
(ICH)
Quality control
Improved and ligand-free copper-catalyzed cyclization for an efficient synthesis of benzimidazoles from
o
-bromoarylamine and nitriles
期刊论文
OAI收割
RSC ADVANCES, 2024, 卷号: 14, 期号: 10, 页码: 6906-6916
作者:
Bonku, Emmanuel Mintah
;
Qin, Hongjian
;
Odilov, Abdullajon
;
Abduahadi, Safomuddin
;
Guma, Samuel Desta
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/05/07
Efficient Large-Scale Process for Tecovirimat via Reactive Distillation for the Preparation of Cycloheptatriene
期刊论文
OAI收割
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2023, 页码: 8
作者:
Bonku, Emmanuel Mintah
;
Qin, Hongjian
;
Odilov, Abdullajon
;
Yang, Feipu
;
Xing, Xinglong
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2023/12/08
tecovirimat
monkeypox
cycloheptatriene
antiviral drug
reactive distillation