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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [3]
化学研究所 [2]
上海生物化学与细胞生... [2]
合肥物质科学研究院 [1]
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OAI收割 [8]
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期刊论文 [8]
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2024 [1]
2023 [2]
2022 [1]
2013 [1]
2012 [1]
2011 [1]
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Oncology [1]
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Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido [2,3-
d
]pyrimidin-7-one-based SOS1 inhibitor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107, 页码: 9
作者:
Wang, Kun
;
Zhou, Zehui
;
Ma, Xinyi
;
Xu, Jiahang
;
Xu, Wangyang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/07/12
SOS1
KRAS mutation
PROTAC
Anti-cancer activity
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
Design, Synthesis, and Bioevaluation of Pyrido[2,3-d]pyrimidin-7-ones as Potent SOS1 Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 183-190
作者:
Liu, Meiying
;
Zhou, Guizhen
;
Su, Wenhong
;
Gu, Yuejiao
;
Gao, Mingshan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/27
KRAS mutation
SOS1-KRAS interaction
SOS1 inhibitor
combination therapy
Safety and Efficacy of D-1553 in Patients with KRAS G12C Mutated Non-Small Cell Lung Cancer: A Phase 1 Trial
期刊论文
OAI收割
JOURNAL OF THORACIC ONCOLOGY, 2022, 卷号: 17
作者:
Lu, S.
;
Jian, H.
;
Zhang, Y.
;
Song, Z.
;
Zhao, Y.
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/12/23
Non-small cell lung cancer
KRAS G12C mutation
Small molecular inhibitor
Multiplex detection of KRAS and BRAF mutations using cationic conjugated polymers
期刊论文
OAI收割
CHINESE SCIENCE BULLETIN, 2013, 卷号: 58, 期号: 8, 页码: 873-878
作者:
Xing BaoLing
;
Song JinZhao
;
Ge SuMei
;
Tang ZhengHua
;
Liu MengLu
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/04/09
Conjugated Polymers
Dna Mutation
Kras
Braf
Sensors
Lung Adenocarcinomas with HER2-Activating Mutations Are Associated with Distinct Clinical Features and HER2/EGFR Copy Number Gains
期刊论文
OAI收割
JOURNAL OF THORACIC ONCOLOGY, 2012, 卷号: 7, 期号: 1, 页码: 85-89
作者:
Li, CG
;
Sun, YH
;
Fang, R
;
Han, XK
;
Luo, XY
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2015/07/22
HER2
Lung adenocarcinoma
Mutation
Copy number
EGFR
KRAS
Rapid and Sensitive Detection of KRAS Mutation After fast-COLD-PCR Enrichment and High-resolution Melting Analysis
期刊论文
OAI收割
DIAGNOSTIC MOLECULAR PATHOLOGY, 2011, 卷号: 20, 期号: 2, 页码: 81-89
作者:
Song, Chen
;
Milbury, Coren A.
;
Li, Jin
;
Liu, Pingfang
;
Zhao, Meiping
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/04/09
Cold-pcr
Hrm
Kras
Lung Adenocarcinoma
Mutation Detection
Spectrum of LKB1, EGFR, and KRAS Mutations in Chinese Lung Adenocarcinomas
期刊论文
OAI收割
JOURNAL OF THORACIC ONCOLOGY, 2010, 卷号: 5, 期号: 8, 页码: 1130-1135
作者:
Gao, B
;
Sun, YH
;
Zhang, JH
;
Ren, Y
;
Fang, R
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2015/07/22
Chinese lung adenocarcinoma
LKB1
EGFR
KRAS
Mutation