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浏览/检索结果: 共52条，第1-10条 帮助

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LPS exacerbates TRPV4-mediated itch through the intracellular TLR4-PI3K signalling 期刊论文  OAI收割
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2024, 卷号: 28, 期号: 13, 页码: 9
作者:  Hao, Yanping;  Wu, Liyan;  Wang, Yuhui;  Shan, Dongmei;  Liu, Yifei
  |  收藏  |  浏览/下载：16/0  |  提交时间：2024/08/22
Pea-Pod-like Carbon Microspheres Encapsulated by Graphene-like Carbon Nitride for Enhanced Thermal Conductivity in Polyimide Films 期刊论文  OAI收割
ACS APPLIED POLYMER MATERIALS, 2022
作者:  Liu, Shuaishuai;  Wang, Yanyan;  Xiao, Chao;  Jiang, Miao;  Ding, Xin
  |  收藏  |  浏览/下载：42/0  |  提交时间：2022/12/23
Hyccin/FAM126A deficiency reduces glial enrichment and axonal sheath, which are rescued by overexpression of a plasma membrane- targeting PI4KIIIa in Drosophila 期刊论文  OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 卷号: 589, 页码: 71-77
作者:  Zhang, Qichao;  Zhang, Baozhu;  Lim, Nastasia K. H.;  Zhang, Xiao;  Meng, Shiquan
  |  收藏  |  浏览/下载：36/0  |  提交时间：2022/06/15
Structural Determinants for Light-Dependent Membrane Binding of a Photoswitchable Polybasic Domain 期刊论文  OAI收割
ACS SYNTHETIC BIOLOGY, 2021, 卷号: 10
作者:  Li, Ling;  He, Lian;  Wu, Bo;  Yu, Chuandi;  Zhao, Hongxin
  |  收藏  |  浏览/下载：38/0  |  提交时间：2021/04/26
Discovery of 2-(5-(quinolin-6-yl)-1,3,4-oxadiazol-2-yl)acetamide derivatives as novel PI3K alpha inhibitors via docking-based virtual screening 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 9
作者:  Gu, Dongyan;  Cheng, Gang
  |  收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:  Xiang, Hao-Yue;  Wang, Xiang;  Chen, Yan-Hong;  Zhang, Xi;  Tan, Cun
  |  收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24
Design, synthesis and antiproliferative activity evaluation of a series of pyrrolo [2,1-f] [1,2,4] triazine derivatives 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 12, 页码: 4
作者:  Xiang, Hao-Yue;  Chen, Yan-Hong;  Wang, Yi;  Zhang, Xi;  Ding, Jian
  |  收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01
Discovery of 6 '-chloro-N-methyl-5 '-(phenylsulfonamido)-[3,3 '-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 188
作者:  Liang, Xiaofei;  Jiang, Zongru
  |  收藏  |  浏览/下载：41/0  |  提交时间：2020/11/26
Toll-Like Receptor 7 Activation Enhances CD8+T Cell Effector Functions by Promoting Cellular Glycolysis 期刊论文  OAI收割
FRONTIERS IN IMMUNOLOGY, 2019, 卷号: 10, 页码: 14
作者:  Li, Qian;  Yang, Yan;  Liu, Jia;  Huang, Xuan;  Zhang, Xiaoyong
  |  收藏  |  浏览/下载：18/0  |  提交时间：2019/10/17
Simultaneous inhibition of PI3K alpha and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer 期刊论文  OAI收割
CANCER BIOLOGY & MEDICINE, 2019, 卷号: 16, 期号: 1, 页码: 66-+
作者:  Wang, Yuxiang;  Li, Xian;  Liu, Xueling;  Chen, Yi;  Yang, Chunhao
  |  收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01
PI3K alpha  CDK4/6  KRAS  NSCLC  CYH33